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Postion:Product Catalog >BI-78D3
BI-78D3
  • BI-78D3

BI-78D3 NEW

Price $52 $85 $172
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: BI-78D3 CAS No.: 883065-90-5
Purity: 97.89% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameBI-78D3
DescriptionBI-78D3, a competitive JNK inhibitor. IC50 of BI-78D3 is 280 nM that displays > 100 fold selectivity over p38α, and have no activity at mTOR and PI-3K.
Cell ResearchCells are subjected to a dose range of doxorubicin concentrations in the presence or absence of a non-toxic dose (10 nM) of the small molecule JIP1-inhibitor BI-78D3. (Only for Reference)
In vitroBI-78D3 Inhibits JNK interacting protein 1 (JIP1)-JNK binding and prevents JNK substrate phosphorylation[2].
In vivoIn animal studies, BI-78D3 not only blocks JNK dependent Con A-induced liver damage but also restores insulin sensitivity in mouse models of type 2 diabetes[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationEthanol : 1.9 mg/mL (5 mM)
DMSO : 37.9 mg/mL (100 mM)
KeywordsBI-78D-3 | inhibit | BI-78D3 | BI 78D3 | Inhibitor | BI78D3 | JNK
Inhibitors RelatedJNK-IN-13 | Urolithin B | Astragaloside IV | SKLB-163 | SP600125 | (-)-Bornyl acetate | Anisomycin | SR-3306 | (E)-Ferulic acid methyl ester | Bentamapimod | Ginsenoside Re | TCS JNK 5a
Related Compound LibrariesHighly Selective Inhibitor Library | Bioactive Compound Library | Anti-Neurodegenerative Disease Compound Library | Pain-Related Compound Library | Anti-Diabetic Compound Library | Kinase Inhibitor Library | Inhibitor Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Liver Cancer Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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