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Postion:Product Catalog >Biochemical Engineering>Inhibitors>BI-0474
BI-0474
  • BI-0474
  • BI-0474
  • BI-0474
  • BI-0474

BI-0474 NEW

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Package 10mg 50mg 100mg
Min. Order: 5mg
Supply Ability: 10g
Update Time: 2024-10-29

Product Details

Product Name: BI-0474 CAS No.: 2750570-55-7
Min. Order: 5mg Purity: 98%+ HPLC HNMR
Supply Ability: 10g Release date: 2024/10/29

BI-0474 is a potent KRASG12C inhibitor with an IC50 value of 7.0 nM for the GDP-KRAS::SOS1 protein-protein interaction. BI-0474 exhibits good anti-proliferative activity against NCI-H358 cells carrying the G12C mutation. BI-0474 also shows good anti-tumour activity in non-small cell lung cancer xenograft models.




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