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Postion:Product Catalog >Biochemical Engineering>Inhibitors>BI-2493
BI-2493
  • BI-2493

BI-2493 NEW

Price $630 $1550 $2480
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-15

Product Details

Product Name: BI-2493 CAS No.: 2937344-16-4
Purity: 99.49% Supply Ability: 10g
Release date: 2024/11/15

Product Introduction

Bioactivity

名稱BI-2493
描述BI-2493 is a highly selective pan-KRAS inhibitor and structural analog of BI-2865.BI-2493 exhibits antitumor activity and inhibits tumor cell growth and can be used in the study of cancerous diseases.BI-2493 is a highly selective pan-KRAS inhibitor and structural analog of BI-2865.
體外活性METHODS: ASPC1, HPAC and H727 cells were treated with BI-2493 (Log (1-4nM)), and cell viability was detected after 72 hours. RESULTS BI-2493 inhibited the growth of ASPC1, HPAC and H727 cells. [1]
體內(nèi)活性METHODS: A cell line-derived xenograft model was established, and mice were randomly assigned according to tumor size (n = 7-8 mice per treatment group) and treated with BI-2493 (10-90 mg/kg, orally twice daily) . RESULTS BI-2493 attenuated tumor growth in xenograft model mice. [1]
存儲(chǔ)條件Shipping with blue ice.
溶解度DMSO : 60 mg/mL (129.99 mM), Sonication and heating are recommended.
關(guān)鍵字BI2493 | BI 2493 | BI-2493
相關(guān)產(chǎn)品Adagrasib | (S)-AMG-510 | CCG-257081 | Ketoconazole | Deltarasin | ZCL278 | MRTX1133 | Salirasib | RMC-6236 | (S)-(-)-Perillyl alcohol | CASIN | Sotorasib
相關(guān)庫疼痛相關(guān)化合物庫 | 經(jīng)典已知活性庫 | 膜蛋白靶向化合物庫 | 激酶抑制劑庫 | 已知活性化合物庫 | GPCR靶點(diǎn)分子庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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