Bemnifosbuvir hemisulfate NEW
| Price | $53 | $118 | $193 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-11 |
Product Details
| Product Name: Bemnifosbuvir hemisulfate | CAS No.: 2241337-84-6 |
| Purity: 99.98% | Supply Ability: 10g |
| Release date: 2024/11/11 |
Product Introduction
Bioactivity
| 名稱 | Bemnifosbuvir hemisulfate |
| 描述 | Bemnifosbuvir hemisulfate (AT-527) is a potent inhibitor of HCV virus replication. |
| 體外活性 | The potent in vitro activity of AT-511, the free base of bemnifosbuvir hemisulfate, against several coronaviruses, including SARS-CoV-2. In normal human airway epithelial cells, the concentration of AT-511 required to inhibit replication of SARS-CoV-2 by 90% (EC90) was 0.47?μM, very similar to its EC90 against human coronavirus (HCoV)-229E, HCoV-OC43, and SARS-CoV in Huh-7 cells[1]. |
| 體內(nèi)活性 | When given orally to rats and monkeys, bemnifosbuvir hemisulfate preferentially delivered high levels of AT-9010 in the liver in vivo.These favorable preclinical attributes support bemnifosbuvir hemisulfate may increase SVR rates[2]. |
| 存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 170 mg/mL (269.60 mM), Sonication is recommended. |
| 關(guān)鍵字 | Inhibitor | antiviral | phosphoramidate | HCV | nucleotide | Bemnifosbuvir | SARS-CoV | pangenotypic | Bemnifosbuvir hemisulfate | AT 527 | Bemnifosbuvir Hemisulfate | guanosine | SARS coronavirus | AT527 | Hepatitis C virus | inhibit |
| 相關(guān)產(chǎn)品 | Nirmatrelvir | EIDD-1931 | Remdesivir | Ribavirin | Silymarin | Umifenovir hydrochloride | Sofosbuvir | Hydroxychloroquine | Ritonavir | Chloroquine phosphate | Artemisinin | Favipiravir |
| 相關(guān)庫 | 經(jīng)典已知活性庫 | 藥物功能重定位化合物庫 | NO PAINS 化合物庫 | 口服活性化合物庫 | 臨床期小分子藥物庫 | 已知活性化合物庫 | 共價抑制劑庫 | 抗感染化合物庫 | 核苷類化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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