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Postion:Product Catalog >API>Synthetic Anti-infective Drugs>Antiviral drugs>Acyclovir
Acyclovir
  • Acyclovir

Acyclovir NEW

Price $39 $51 $80
Package 25mg 50mg 100mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Acyclovir CAS No.: 59277-89-3
Purity: 100.00% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameAcyclovir
DescriptionAcyclovir (Aciclovir) is a synthetic analog of the purine nucleoside, guanosine, with potent antiviral activity against herpes simplex viruses type 1 and 2, varicella-zoster virus and other viruses of the herpesvirus family.
Kinase AssayTotal AMPK activity is measured using the method of Dagher et al. AMPK activity is quantified in the resuspended pellet as incorporation of?32P from [γ-32P]ATP (10 GBq/mmol) into a synthetic peptide with the specific target sequence for AMPK, the SAMS peptide. Radioactivity is measured using a liquid scintillation counter. Protein content in the solution containing the resupended (NH4)2SO4 pellet is determined using the Bradford method.
In vitroAcyclovir sensitivity of herpes simplex virus isolates is determined in a plaque-reduction assay in Vero cells. IC50 Values are consistently 2-3 fold lower in B2 compared with the H strain of Vero cells. HSV Type 2 strains are 2-10-fold less sensitive than Type 1 strains[2].
In vivolow-dose oral acyclovir may be effective in the prevention of HSV infection during OKT3 treatment of seropositive patients. Continuation of acyclovir prophylaxis for two to four weeks following the conclusion of OKT3 therapy may prevent occurrence of delayed infections[3].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 55 mg/mL (244.23 mM)
Ethanol : < 1 mg/mL (insoluble or slightly soluble)
Keywordsinhibit | Inhibitor | Herpes simplex virus | thymidine | triphosphate | HSV | immunosuppression | DNA | Antibiotic | Acyclovir | anti-herpetic | Apoptosis | kinase | antibody | polymerase | Bacterial
Inhibitors RelatedNeomycin sulfate | Stavudine | Ampicillin sodium | Kanamycin sulfate | Sulfamethoxazole sodium | Guanidine hydrochloride | Doxycycline | Tributyrin | Thymidine | Dimethyl sulfoxide | Salicylic acid | Oleic acid
Related Compound LibrariesBioactive Compound Library | Anti-Cancer Clinical Compound Library | Anti-Viral Compound Library | Anti-Cancer Approved Drug Library | FDA-Approved Drug Library | Anti-Aging Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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