λ-Cyhalothrin NEW
| Price | $41 |
| Package | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: λ-Cyhalothrin | CAS No.: 91465-08-6 |
| Purity: 99.94% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | λ-Cyhalothrin |
| Description | λ-Cyhalothrin (Icon) is a type II synthetic pyrethroid insecticide featuring a high-efficiency, broad-spectrum formula with an α-cyano group. It is employed across various applications for controlling a wide array of pests. As a neurotoxin, λ-Cyhalothrin acts on sodium channels in neuron membranes within the central nervous system. |
| In vitro | λ-Cyhalothrin's toxicity mechanism involves delaying sodium channel inactivation, leading to prolonged depolarization of the nerve membrane. This compound causes membrane depolarization, influx of calcium ions, and neurotransmitter release in rat brain synaptosomes[1]. Additionally, λ-Cyhalothrin exhibits estrogenic qualities, acting as a xenoestrogen that promotes proliferation of human breast carcinoma cells in vitro[1]. It is extensively utilized for controlling pests (fleas, cockroaches, flies, and ants)[1] and is highly effective against Anopheles species, known for transmitting malaria[1]. |
| In vivo | The investigation assesses the impact of λ-Cyhalothrin (i.p.) on memory, movement activity, and coordination in mice subjected to bilateral clamping of the carotid arteries (BCCA). It was found that neither memory nor coordination was negatively affected by BCCA or λ-Cyhalothrin. However, a notable decline in exploratory locomotor activity was observed in the BCCA/LCH group, and spontaneous movement activity significantly decreased in the BCCA/λ-Cyhalothrin group. Furthermore, when exposed to λ-Cyhalothrin in the presence of BCCA, a decrease in motor activity was evident in mice during two subsequent 30-minute sessions[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 60 mg/mL (133.38 mM), Sonication is recommended. |
| Keywords | Na channels | Inhibitor | λ Cyhalothrin | Na+ channels | inhibit | Parasite | Sodium Channel | depolarization | λCyhalothrin | pesticide | pyrethroid | choreoatetosis | acaricide | λ-Cyhalothrin | Insecticide | neurotoxin | salivation | α-cyano |
| Inhibitors Related | Phenytoin sodium | Kaempferol | Procaine | Hydroxychloroquine | Metronidazole | Nitazoxanide | Doxycycline | Chloroquine phosphate | Lidocaine hydrochloride | L-Aspartic aicd sodium | Artemisinin | Benzyl benzoate |
| Related Compound Libraries | Pesticide Compound Library | Anti-Parasitic Compound Library | Pain-Related Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Sodium Channel Targeted Library | Neuroprotective Compound Library | Bioactive Compounds Library Max | Ion Channel Targeted Library | Anti-Infection Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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