- 3-Chloroaniline
-
- $0.00 / 25KG
-
2025-02-21
- CAS:108-42-9
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 50000KG/month
- 3-Chloroaniline
-
- $0.00 / 25KG
-
2025-02-21
- CAS:108-42-9
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 50000KG/month
- 3-Chloroaniline
-
- $1.00 / 200KG
-
2025-02-19
- CAS:108-42-9
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 10 mt
Related articles - 3-Chloroaniline
- 3-chloroaniline is a colorless to light amber liquid with a sweet odor. m.p.-11～-9 ℃, b.p.230～231 ℃ (95～96 ℃/1.47 kPa), n20D 1....
- Nov 9，2021
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| | 3-Chloroaniline Basic information |
| | 3-Chloroaniline Chemical Properties |
| Melting point | −11-−9 °C(lit.) | | Boiling point | 95-96 °C11 mm Hg(lit.) | | density | 1.206 g/mL at 25 °C(lit.) | | vapor pressure | 1 mm Hg ( 63.5 °C) | | refractive index | n20/D 1.594(lit.) | | Fp | 255 °F | | storage temp. | Store below +30°C. | | solubility | 6.2g/l | | form | Liquid | | pka | 3.46(at 25℃) | | color | Clear pale yellow to brown | | PH | 7.3 (H2O)(saturated aqueous solution) | | Odor | Characteristic odour | | Water Solubility | 6.8 g/L (20 ºC) | | Decomposition | 190°C | | Merck | 14,2118 | | BRN | 605969 | | Dielectric constant | 13.4（19℃） | | Stability: | Material darkens in storage with no loss in purity, Material Darkens In Storage | | LogP | 0.77-2.03 at 25-30℃ | | CAS DataBase Reference | 108-42-9(CAS DataBase Reference) | | NIST Chemistry Reference | m-Chloroaniline(108-42-9) | | EPA Substance Registry System | m-Chloroaniline (108-42-9) |
| | 3-Chloroaniline Usage And Synthesis |
| Description | m-Chloroaniline
is used as an intermediate for pesticides, pharmaceuticals,
and dyes. It is produced by lowpressure
hydrogenation of 3-chloronitrobenzene
in the liquid phase with noble metal and/or noble
metal sulfide catalysts. The addition of metal oxides
to the reaction helps avoid dehalogenation.
The yield is approximately 98 %. | | Chemical Properties | 3-Chloroaniline is a clear pale yellow to brown liquid, which becomes darker during storage, insoluble in water, but soluble in ethanol, ether and acid solution. | | Application | 3-Chloroaniline is the intermediate of the herbicide chloraniline, and the intermediate of the pharmaceutical diuretic antihypertensive drug hydrochlorothiazide, and can be used to produce azo dyes.
3-Chloroaniline was the only aniline compound to increase plasmaALT/GPT activity at 48 h. It is employed in the bioaugmentation of activated sludge. | | Uses | 3-Chlorobenzenamine is used in the synthesis of pyrimidoazepine analogs as serotonin 5-HT2A and 5-HT2C receptor ligands for the treatment of obesity. Also used in the synthesis of novel COX-2 inhibito
rs. | | Preparation | 3-Chloroaniline is obtained by reducing 3-Nitrochlorobenzene with iron powder in the presence of ferrous sulfate. | | Synthesis Reference(s) | Tetrahedron Letters, 36, p. 7313, 1995 DOI: 10.1016/0040-4039(95)01474-V | | General Description | Colorless to light amber liquid with a sweet odor. | | Air & Water Reactions | Sensitive to prolonged exposure to air and light and tends to darken during storage. Insoluble in water. | | Reactivity Profile | 3-Chloroaniline is incompatible with acids, acid chlorides, acid anhydrides, chloroformates and strong oxidizing agents. | | Fire Hazard | 3-Chloroaniline is combustible. | | Flammability and Explosibility | Non flammable | | Safety Profile | Poison by ingestion,
skin contact, subcutaneous, and intravenous
routes. Mutation data reported. When
heated to decomposition it emits toxic
fumes of Cland NOx. See also ANILINE
DYES. |
| | 3-Chloroaniline Preparation Products And Raw materials |
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