|
|
| | 1-(5-Methyl-2-thienyl)ethan-1-one Basic information |
| | 1-(5-Methyl-2-thienyl)ethan-1-one Chemical Properties |
| Melting point | 24-28 °C(lit.) | | Boiling point | 65-67 °C1 mm Hg(lit.) | | density | 1.106 g/mL at 25 °C(lit.) | | FEMA | 4643 | 2-ACETYL-5-METHYLTHIOPHENE | | refractive index | n20/D 1.561(lit.) | | Fp | >230 °F | | storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | form | Low Melting Crystalline Mass, Powder or Crystals | | Specific Gravity | 1.119 | | color | White to pale yellow | | Odor | at 1.00 % in propylene glycol. sweet spicy honey hawthorn almond acacia hyacinth caramellic graham cracker | | Odor Type | spicy | | Sensitive | Light Sensitive | | JECFA Number | 2107 | | BRN | 110854 | | LogP | 2.04 | | CAS DataBase Reference | 13679-74-8(CAS DataBase Reference) | | NIST Chemistry Reference | 2-Acetyl-5-methylthiophene(13679-74-8) |
| Hazard Codes | Xn,Xi | | Risk Statements | 20/21/22 | | Safety Statements | 36/37-22 | | RIDADR | UN 3335 | | WGK Germany | 3 | | RTECS | OB4972000 | | Hazard Note | Irritant | | HazardClass | STENCH | | HS Code | 29349990 |
| | 1-(5-Methyl-2-thienyl)ethan-1-one Usage And Synthesis |
| Chemical Properties | white to light yellow crystal powder | | Uses | 2-Acetyl-5-methylthiophene may be used in the preparation of:
- 2-ethyl-5-methylthiophene
- (5-methylthiophen-2-yl)glyoxal
- (2E)-1-(5-methylthiophen-2-yl)-3-(pyridin-3-yl)prop-2-en-1-one
- ethyl 3-(5-methylthiophen-2-yl)-3-oxopropanoate
| | Definition | ChEBI: 2-acetyl-5-methylthiophene is a thiophene that is substituted by acetyl and methyl groups at positions 2 and 5, respectively. It has a role as a flavouring agent. It is an aromatic ketone, a member of thiophenes and a methyl ketone. | | General Description | 2-Acetyl-5-methylthiophene is a volatile organic compound formed during the reaction between L-cysteine and dihydroxyacetone in glycerine or triglyceride solvent system. It can be prepared by reacting 2-methylthiophene with acetic anhydride. 2-Acetyl-5-methylthiophene undergoes palladium-catalyzed cross-coupling reaction with aryl bromides to form C-4 arylated product. It reacts with 1,2-bis(5-formyl-2-methylthiophen-3-yl)cyclopentene via Aldol condensation to form a chalcone with photochromic property. The standard molar enthalpies of combustion, formation and vaporization of 2-acetyl-5-methylthiophene are 4341.9 ± 1.8kJ/mol, 158.0 ± 2.1kJ/mol and 62.0 ± 2.6kJ/mol, respectively. | | Safety Profile | A poison by
intraperitoneal route. A flammable liquid.
When heated to decomposition it emits
toxic vapors of SOx. |
| | 1-(5-Methyl-2-thienyl)ethan-1-one Preparation Products And Raw materials |
|