- MOSLOFLAVONE
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- $40.00 / 5mg
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2024-11-19
- CAS:740-33-0
- Min. Order:
- Purity: ≥95%
- Supply Ability: 10g
- Mosloflavone
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- $0.00 / 5mg
-
2023-02-24
- CAS:740-33-0
- Min. Order: 5mg
- Purity: ≥98%(HPLC)
- Supply Ability: 10 g
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| | MOSLOFLAVONE Basic information |
| Product Name: | MOSLOFLAVONE | | Synonyms: | 5-Hydroxy-6,7-dimethoxy-2-phenyl-4H-1-benzopyran-4-one;5-Hydroxy-6,7-diMethoxy-2-phenyl-4H-chroMen-4-one;5-Hydroxy-6,7-diMethoxyflavone;5-Hydroxy-6,7-diMethoxylflavone;4H-1-Benzopyran-4-one, 5-hydroxy-6,7-dimethoxy-2-phenyl-;Mosloflavone( 5-Hydroxy-6,7-dimethoxyflavone);HEVs,Inhibitor,HRV,HRVs,MOSLOFLAVONE,Rhinovirus,Enterovirus,inhibit,P. aeruginosa,Bacterial,Enterovirus 71,EV-71,HEV,biocide | | CAS: | 740-33-0 | | MF: | C17H14O5 | | MW: | 298.29 | | EINECS: | | | Product Categories: | Di-substituted Flavones | | Mol File: | 740-33-0.mol |  |
| | MOSLOFLAVONE Chemical Properties |
| Melting point | 163-164℃ (chloroform , acetone ) | | Boiling point | 508.5±50.0 °C(Predicted) | | density | 1.321±0.06 g/cm3 (20 ºC 760 Torr) | | storage temp. | 2-8°C | | solubility | Soluble in DMSO | | pka | 6.32±0.40(Predicted) | | form | Solid | | color | Light yellow to yellow | | biological source | plant | | Water Solubility | water: slightly soluble |
| | MOSLOFLAVONE Usage And Synthesis |
| Uses | Mosloflavon is a natural product derived from plant source th at finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research. | | Definition | ChEBI: Mosloflavone is a member of flavonoids and an ether. | | Biological Activity | Mosloflavanone exhibits potent anti-EV71 activity by reducing visible cytopathic effects and suppressing virus replication during the initial infection phase. It also hinders the expression of the viral VP2 protein, thereby impeding viral capsid protein synthesis. Additionally, Mosloflavone demonstrates significant anti-inflammatory potential through the inhibition of TNF-α and IL-1β, with IC50 values of 16.4 μM and 6.4 μM, respectively. It shows a dose-dependent reduction in TNF-α, IL-1β, and iNOS levels in the supernatant of the mouse macrophage cell line J774A. This compound holds promise as a foundational element in the quest for treatments targeting inflammatory and immunomodulatory diseases. |
| | MOSLOFLAVONE Preparation Products And Raw materials |
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