CVT-6883 manufacturers
- GS-6201
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- $37.00 / 1mg
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2024-11-19
- CAS:752222-83-6
- Min. Order:
- Purity: 99.74%
- Supply Ability: 10g
- CVT 6883
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- $1.00 / 1g
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2020-01-13
- CAS:752222-83-6
- Min. Order: 1g
- Purity: 99%
- Supply Ability: 1ton
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| CVT-6883 Basic information |
Product Name: | CVT-6883 | Synonyms: | CVT-6883;3-Ethyl-3,9-dihydro-1-propyl-8-[1-[[3-(trifluoroMethyl)phenyl]Methyl]-1H-pyrazol-4-yl]-1H-purine-2,6-dione;3-Ethyl-1-propyl-8-(1-(3-(trifluoromethyl)benzyl)-1H-pyrazol-4-yl)-1H-purine-2,6(3H,8H)-dione;3-Ethyl-1-propyl-8-[1-(3-trifluoromethyl-benzyl)-1H-pyrazol-4-yl]-3,7-dihydro-purine-2,6-dione;GS6201 CVT6883;GS-6201;GS 6201; GS6201; GS6201; CVT6883; CVT-6883;1H-Purine-2,6-dione, 3-ethyl-3,9-dihydro-1-propyl-8-[1-[[3-(trifluoromethyl)phenyl]methyl]-1H-pyrazol-4-yl]- | CAS: | 752222-83-6 | MF: | C21H21F3N6O2 | MW: | 446.43 | EINECS: | 200-258-5 | Product Categories: | | Mol File: | 752222-83-6.mol |  |
| CVT-6883 Chemical Properties |
Boiling point | 639.6±65.0 °C(Predicted) | density | 1.44 | storage temp. | Store at -20°C | solubility | DMSO: soluble | form | A solid | pka | 7.69±0.70(Predicted) | color | White to light brown |
| CVT-6883 Usage And Synthesis |
Uses | 3-Ethyl-3,9-dihydro-1-propyl-8-[1-[[3-(trifluoromethyl)phenyl]methyl]-1H-pyrazol-4-yl]-1H-purine-2,6-dione, is a novel selective, high-affinity A2B adenosine receptor (AR) antagonist, used for the treatment of inflammatory and angiogenic diseases. | Biological Activity | GS-6201 (CVT-6883) is a potent and selective A2B adenosine receptor (A2BAdoR) antagonist. GS-6201 reduces caspase-1 activity in the heart and leads to a more favorable cardiac remodeling in a mouse model of non-reperfused myocardial infarction. Also GS-6201 attenuated vascular remodeling and hypertension in mouse model. | storage | Store at -20°C |
| CVT-6883 Preparation Products And Raw materials |
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