| | QUAZEPAM Basic information |
| Product Name: | QUAZEPAM | | Synonyms: | dormalin;oniria;prosedar;quazepam;quazium;sch16134;QUAZEPAM CIV (200 MG);2H-1,4-Benzodiazepine-2-thione | | CAS: | 36735-22-5 | | MF: | C17H11ClF4N2S | | MW: | 386.79 | | EINECS: | 253-179-4 | | Product Categories: | | | Mol File: | 36735-22-5.mol |  |
| | QUAZEPAM Chemical Properties |
| RIDADR | 3249 | | HazardClass | 6.1(b) | | PackingGroup | III | | HS Code | 2933996500 | | Toxicity | LD50 in mice (mg/kg): >1370 i.v., >5000 orally (Orgini); LD50 in male, female mice, rats (mg/kg): 845, 921, 3072, 2749 i.p. (Black) |
| | QUAZEPAM Usage And Synthesis |
| Description | Quazepam is a rapidly acting, short term hypnotic reported to exhibit a low
incidence of side effects. | | Originator | Schering (USA) | | Uses | Quazepam is a benzodiazepine derivative drug and is known to bind nonspecifically to benzodiazepine receptors, which affects muscle relaxation, anticonvulsant activty, motor coordination and memory. Quazepam is known to induce motor impairment and exerts hypnotic properties. Quazepam is often used for the treatment of insomina. | | Definition | ChEBI: Quazepam is a benzodiazepine. | | Brand name | Doral (Questcor). | | General Description | Quazepam (Doral) and its active metabolitesreportedly are relatively selective for the benzodiazepinemodulatory site on GABAA receptors with α1 subunitand are hypnotic agents. Quazepam is metabolized by oxidation to the 2-oxo compound and then N-dealkylation.Both metabolites are active; the first reportedly is the morepotent and selective. Thereafter, 3-hydroxylation and glucuronidationoccur. |
| | QUAZEPAM Preparation Products And Raw materials |
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