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| | AC-LEHD-AFC Basic information |
| Product Name: | AC-LEHD-AFC | | Synonyms: | N-ACETYL-LEU-GLU-HIS-ASP 7-AMIDO-4-TRIFLUOROMETHYLCOUMARIN;N-ACETYL-LEU-GLU-HIS-ASP-(7-AMINO-4-TRIFLUOROMETHYLCOUMARIN);N-ACETYL-LEU-GLU-HIS-ASP-7-AMINO-4-TRIFLUOROMETHYLCOUMARIN AFC;AC-LEU-GLU-HIS-ASP-7-AMINO-4-TRIFLUORO-METHYLCOUMARIN;AC-LEU-GLU-HIS-ASP-AFC;CASPASE-9 SUBSTRATE I, FLUOROGENIC;CASPASE 9 SUBSTRATE 1F, FLUOROGENIC;AC-LEHD-AFC | | CAS: | 210345-03-2 | | MF: | C33H38F3N7O11 | | MW: | 765.69 | | EINECS: | | | Product Categories: | Caspases/Apoptosis;peptide | | Mol File: | 210345-03-2.mol |  |
| | AC-LEHD-AFC Chemical Properties |
| Boiling point | 1211.9±65.0 °C(Predicted) | | density | 1.457±0.06 g/cm3(Predicted) | | storage temp. | −20°C | | solubility | DMSO/DMF: 20 mM | | form | powder | | pka | 4.07±0.10(Predicted) | | color | white | | Water Solubility | Soluble to 1 mg/ml in water |
| | AC-LEHD-AFC Usage And Synthesis |
| Uses | Ac-LEHD-AFC Trifluoroacetic Acid Salt is a fluorogenic substrate that is cleaved by caspases (4,5 and 9). This activity is quantified by fluorescent detection of free AFC. Caspase-9 activation is critical for intrinsic cell death. | | Biological Activity | Fluorogenic caspase substrate. Analog of the caspase-9 substrate, LEHD-AFC. |
| | AC-LEHD-AFC Preparation Products And Raw materials |
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