| Company Name: |
Yichang Zhongyitai Trading Co., Ltd.
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| Tel: |
0717-6449896 13886658719 |
| Email: |
root@zhongyitai.com |
| Products Intro: |
Product Name:13(S)-HOD [13(S)-hydroxy-9(Z),11(E)-octadecadienoic acid]
CAS:29623-28-7
Purity:97+%,GC-MS/HPLC Package:1Mg
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| Company Name: |
Alfa Chemistry
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| Tel: |
1-516-6625404 |
| Email: |
support@alfa-chemistry.com |
| Products Intro: |
Product Name:13(S)-hydroxy-9(Z),11(E)-octadecadienoic acid
CAS:29623-28-7
Purity:98%+ Package:1g;10g;100g;1KG;5KG
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13(S)-HYDROXYOCTADECA-9Z,11E-DIENOIC ACID manufacturers
- (S)-Coriolic acid
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- $389.00 / 100μg
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2025-05-08
- CAS:29623-28-7
- Min. Order:
- Purity: 97.67%
- Supply Ability: 10g
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| | 13(S)-HYDROXYOCTADECA-9Z,11E-DIENOIC ACID Basic information |
| Product Name: | 13(S)-HYDROXYOCTADECA-9Z,11E-DIENOIC ACID | | Synonyms: | 13(S)-HYDROXYOCTADECA-9Z,11E-DIENOIC ACID;(13S,9Z,11E)-13-Hydroxy-9,11-octadecadienoic acid;(9Z,11E,13S)-13-Hydroxy-9,11-octadecadienoic acid;(S)-Coriolic acid;13-Hydroxy-9c,11t-octadecadienoic acid;13(S)-Hydroxyoctadeca-9Z,11E-dienoic acid (13-HODE);13(S)-HOD;13(S)-HODE | | CAS: | 29623-28-7 | | MF: | C18H32O3 | | MW: | 296.44 | | EINECS: | 200-578-6 | | Product Categories: | | | Mol File: | 29623-28-7.mol |  |
| | 13(S)-HYDROXYOCTADECA-9Z,11E-DIENOIC ACID Chemical Properties |
| Boiling point | 422.7±20.0 °C(Predicted) | | density | 0.970±0.06 g/cm3(Predicted) | | Fp | 14 °C | | storage temp. | −20°C | | solubility | DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 1 mg/ml | | form | Clear to light-yellow liquid. | | pka | 4.78±0.10(Predicted) | | color | Colorless to light yellow |
| Hazard Codes | F | | Risk Statements | 11 | | Safety Statements | 7-16 | | RIDADR | UN 1170 3/PG 2 | | WGK Germany | 3 | | HazardClass | 3 |
| | 13(S)-HYDROXYOCTADECA-9Z,11E-DIENOIC ACID Usage And Synthesis |
| Uses | 13(S)-HODE is an inhibitor of tumor cell adhesion in endothelium tissue. 13(S)-HODE is also used to activate GPR132 which may affect autoimmune function and lymph organ size. | | Definition | ChEBI: An HODE (hydroxyoctadecadienoic acid) in which the double bonds are at positions 9 and 11 (E and Z geometry, respectively) and the hydroxy group is at position 13 (with S-configuration). | | Biological Activity | Expression of 15-lipoxygenase-1 (15-LOX-1) and its main product, 13(S)-HODE, are decreased in human colorectal and esophageal cancers. Certain non-steroidal anti-inflammatory drugs (NSAIDs) can induce apoptosis in human colon cancer cells by increased expression of 15-LOX-1, which down-regulates PPAR-delta through 13-HODE. ', 'PPARγ agonist | | in vivo | (S)-Coriolic acid (0-0.6 mg per mouse; Intranasally once a day for 3 consecutive days) causes severe airway dysfunction, airway neutrophilia, mitochondrial dysfunction and epithelial injury[2]. | Animal Model: | BALB/c mice (6-8 weeks)[2] | | Dosage: | 0-0.6 mg per mouse | | Administration: | Intranasally once a day for 3 consecutive days | | Result: | BALB/c mice developed features of mitochondrial dysfunction such as reduction in mitochondrial membrane potential, reduction in complex IV activity in lung mitochondria, and increase in the levels of cytochrome c in lung cytosol.
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| | 13(S)-HYDROXYOCTADECA-9Z,11E-DIENOIC ACID Preparation Products And Raw materials |
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