GRGDSP
| 中文名稱 | GRGDSP |
|---|---|
| 中文同義詞 | 合成線性RGD肽;甘氨酰-精氨酰-甘氨酰-天冬氨酰-絲氨酰-脯氨酸;抑制劑多肽GRGDSP |
| 英文名稱 | glycyl-arginyl-glycyl-aspartyl-seryl-proline |
| 英文同義詞 | glycyl-arginyl-glycyl-aspartyl-seryl-proline;Glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-L-proline;L-Proline, glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-;Glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-L-proline |
| CAS號(hào) | 91037-75-1 |
| 分子式 | C22H37N9O10 |
| 分子量 | 587.58 |
| EINECS號(hào) | |
| 相關(guān)類別 | 標(biāo)準(zhǔn)品;目錄多肽 |
| Mol文件 | 91037-75-1.mol |
| 結(jié)構(gòu)式 |  |
GRGDSP 性質(zhì)
| 儲(chǔ)存條件 | Store at -20°C |
|---|---|
| 溶解度 | 溶于二甲基亞砜 |
| 形態(tài) | 固體 |
| 顏色 | 白色至米白色 |
GRGDSP可用于修飾心血管植入物表面，如血管移植物，促進(jìn)內(nèi)皮化。
GRGDSP 是一種合成的線性RGD肽，是一種整聯(lián)蛋白 (integrin) 抑制劑。Integrin
It is demonstrated that transarterial infusion of GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro integrin-inhibitor which includes RGD-peptide). As a synthetic linear RGD peptide, GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro) can inhibit the adherence of tumor cells to endothelial cells of blood vessels and limit its metastasis. GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro) is used as a soluble integrin-blocking RGD-based peptide. GRGDSP is used widely together with other RGD peptides in integrin research. GRGDSP can be used to modify the surface of cardiovascular implants such as vascular grafts to promote endothelialization.