3-MATIDA manufacturers
- 3-MATIDA
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- $37.00 / 1mg
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2024-11-06
- CAS:518357-51-2
- Min. Order:
- Purity: 99.05%
- Supply Ability: 10g
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| | 3-MATIDA Basic information |
| Product Name: | 3-MATIDA | | Synonyms: | 3-MATIDA;ALPHA-AMINO-5-CARBOXY-3-METHYL-2-THIOPHENEACETIC ACID;α-Amino-5-carboxy-3-methyl-2-thiopheneaceticacid;5-[amino(carboxy)methyl]-4-methylthiophene-2-carboxylic acid;2-Thiopheneacetic acid, α-amino-5-carboxy-3-methyl-;3 MATIDA,3MATIDA;3-MATIDA, 10 mM in DMSO | | CAS: | 518357-51-2 | | MF: | C8H9NO4S | | MW: | 215.23 | | EINECS: | | | Product Categories: | Glutamate receptor | | Mol File: | 518357-51-2.mol |  |
| | 3-MATIDA Chemical Properties |
| storage temp. | Store at +4°C | | solubility | Soluble to 100 mM in 1eq. NaOH and to 50 mM in DMSO | | form | Powder |
| | 3-MATIDA Usage And Synthesis |
| Uses | 3-MATIDA is a potent mGluR-1 antagonist. | | Definition | ChEBI: 5-[amino(carboxy)methyl]-4-methyl-2-thiophenecarboxylic acid is an alpha-amino acid. | | Biological Activity | Potent metabotropic glutamate mGlu 1 receptor antagonist (IC 50 = 6.3 μ M at rat mGlu 1a ). Displays ≥ 40-fold selectivity over other receptors: mGlu 5 , mGlu 2 , mGlu 4a (IC 50 > 300 μ M), NMDA and AMPA (IC 50 = 250 μ M). Neuroprotective in cultured murine cortical cells and rat hippocampal slice cultures in vitro . Reduces the volume of ischemia-induced brain infarcts in rats following systemic administration in vivo . |
| | 3-MATIDA Preparation Products And Raw materials |
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