諾美孕酮
| 中文名稱 | 諾美孕酮 |
|---|---|
| 中文同義詞 | 諾美孕酮;化合物 NOMEGESTROL |
| 英文名稱 | Nomegestrol |
| 英文同義詞 | MELEGESTROL ACETATE;17ALPHA-ACETOXY-6ALPHA-METHYL-19-NOR-PREGN-4,6-DIEN-3,20-DIONE;NOMEGESTROL ACETATE;Nomegestrol;Nomegestrel;17-Hydroxy-6-methyl-19-nor-4,6-pregnadiene-3,20-dione;17-Hydroxy-6-methyl-19-norpregna-4,6-diene-3,20-dione;(8S,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-6,13-dimethyl-1,2,8,9,10,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one |
| CAS號 | 58691-88-6 |
| 分子式 | C21H28O3 |
| 分子量 | 328.45 |
| EINECS號 | 200-258-5 |
| 相關(guān)類別 | 原料藥;原料;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids;Steroid and Hormone |
| Mol文件 | 58691-88-6.mol |
| 結(jié)構(gòu)式 |  |
諾美孕酮 性質(zhì)
| 沸點 | 502.6±50.0 °C(Predicted) |
|---|---|
| 密度 | 1.17±0.1 g/cm3(Predicted) |
| 儲存條件 | 2-8°C |
| 溶解度 | 氯仿：可溶，DMSO：微溶，甲醇：微溶 |
| 形態(tài) | 固體 |
| 酸度系數(shù)(pKa) | 12.99±0.60(Predicted) |
Nomegestrol 是一種有效的，可口服的孕酮，為選擇性的孕酮受體 (progesterone receptor) 完全激動劑，對大鼠子宮孕酮受體的 Kd 值為 5.44 nM，具有很強的抗雌性激素活性，適度的抗雄性激素活性。
Kd: 5.44 nM (Rat uterine progesterone receptor)
Nomegestrol is a progestin, has high binding affinity at progesterone receptor, with a K d of 5.44 nM for rat uterine progesterone receptor. Nomegestrol acetate (NOMAC) is a higly selective progesterone receptor full agonist, but shows no or little binding affinity at other steroid receptors, such as the androgen and glucocorticoid receptors. Nomegestrol acetate has moderate antiandrogenic activity and strong antiestrogenic activity.
安全信息
| 更新日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
|---|---|---|---|---|---|
| 2025/02/08 | HY-105634 | 諾美孕酮 Nomegestrol | 58691-88-6 | 1 mg | 1296元 |