- Valerenic acid
-
- $800.00 / 1g
-
2025-04-08
- CAS:3569-10-6
- Min. Order: 1g
- Purity: 99 %
- Supply Ability: 500 Kg
- Valerenic acid
-
- $1.00 / 1Kg
-
2024-07-20
- CAS:3569-10-6
- Min. Order: 1Kg
- Purity: 98%
- Supply Ability: 20T
- VALERENIC ACID
-
- $2.00 / 1KG
-
2019-07-06
- CAS:3569-10-6
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: customise
|
| | VALERENIC ACID Basic information |
| Product Name: | VALERENIC ACID | | Synonyms: | VALERENIC ACID;VALERENIC ACID WITH HPLC;(E)-3-[(4S)-2,4,5,6,7,7aα-Hexahydro-3,7β-dimethyl-1H-inden-4-yl]-2-methylpropenoic acid;(2E)-3-[(4S,7R,7aR)-2,4,5,6,7,7a-Hexadydro-3,7-dimethyl-1H-inden-4-yl]-2-methyl-2-propenoic acid;2-Propenoic acid, 3-(2,4,5,6,7,7A-hexahydro-3,7-dimethyl-1H-inden-4-yl)-2-methyl-, (4S-(4alpha(E),7beta,7aalpha))-;Valerenic Acid (15 mg);VALERENIC ACID(P);VALERENIC ACID SNAP-N-SHOOT 0.1mg/mL(P) | | CAS: | 3569-10-6 | | MF: | C15H22O2 | | MW: | 234.33 | | EINECS: | | | Product Categories: | Plant Oils, Toxins, Phenolic Acids & Derivatives;Natural Plant Extract;Organic AcidsAnalytical Standards;Alphabetic;Chromatography;Food&Beverage Standards;V | | Mol File: | 3569-10-6.mol |  |
| | VALERENIC ACID Chemical Properties |
| Melting point | 134-139°C | | Boiling point | 374.5±21.0 °C(Predicted) | | density | 1.06±0.1 g/cm3(Predicted) | | storage temp. | −20°C | | solubility | Chloroform (Slightly), Ethanol (Slightly),Methanol (Slightly) | | pka | 4.88±0.19(Predicted) | | form | Solid | | color | White to Off-White | | BRN | 3138020 | | LogP | 5.188 (est) | | CAS DataBase Reference | 3569-10-6(CAS DataBase Reference) |
| WGK Germany | 3 | | RTECS | UD3357700 | | F | 8-10 | | HS Code | 2916205000 |
| | VALERENIC ACID Usage And Synthesis |
| Uses | Valerenic Acid, acts as a subtype-selective GABAA receptor agonist in neonatal rat brainstem preparations. It can be used for the synthesis of Valerena-4,7(11)-diene, a highly active sedative. | | Definition | ChEBI: A monocarboxylic acid that is 2-methylprop-2-enoic acid which is substituted at position 3 by a 3,7-dimethyl-2,4,5,6,7,7a-hexahydro-1H-inden-4-yl group. A bicyclic sesquiterpenoid constituent of the essential oil of the Valerian plant. | | Biological Activity | Positive allosteric modulator of GABA A receptors that displays preference for receptors containing β 2 or β 3 subunits. Directly activates the receptor and also blocks the channel at high concentrations. Displays a sedative and anxiolytic activity in vivo . Also acts as a partial? agonist of 5-HT 5A receptors. | | in vivo | Valerenic acid (1-6 mg/kg i.p. or 10 mg/kg p.o.) decreases the aversion of wild type mice to the lit area[2].
Valerenic acid (10 mg/kg; p.o.) increases the proportion of time 129X1/SvJ mice spent onto the open arms[2]. | | IC 50 | GABAA; 5-HT5A Receptor: 17.2 μM (IC50) |
| | VALERENIC ACID Preparation Products And Raw materials |
|