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絲拉克肽

絲拉克肽

中文名稱絲拉克肽
中文同義詞絲拉克肽;六氟硅酸;促腎上腺皮質(zhì)激素(1-39);絲拉克肽, ≥97% (HPLC);人ACTH (1-39)肽;SERACTIDE、絲拉克肽;促腎上腺皮質(zhì)激素ACTH(1-39);促腎上腺皮質(zhì)激素ACTH(1-39), HUMAN絲拉克肽
英文名稱Seractide
英文同義詞CORTICOTROPIN (HUMAN);CORTICOTROPHIN;CORTICOTROPIN A;H-SER-TYR-SER-MET-GLU-HIS-PHE-ARG-TRP-GLY-LYS-PRO-VAL-GLY-LYS-LYS-ARG-ARG-PRO-VAL-LYS-VAL-TYR-PRO-ASN-GLY-ALA-GLU-ASP-GLU-SER-ALA-GLU-ALA-PHE-PRO-LEU-GLU-PHE-OH;ACTH (1-39) (huMan) Corticotropin;Adrenocorticotropic Hormone (ACTH) (1-39);Seractide acetate;ACTH (1-39), HUMAN
CAS號(hào)12279-41-3
分子式C207H308N56O58S1
分子量4541.07
EINECS號(hào)634-154-0
相關(guān)類別多肽中間體;細(xì)胞生物學(xué);細(xì)胞信號(hào)和神經(jīng)生物學(xué);多肽系列;原料藥;多肽;Peptide;Melanocortin receptor;生化試劑-蛋白質(zhì);藥物多肽
Mol文件12279-41-3.mol
結(jié)構(gòu)式絲拉克肽 結(jié)構(gòu)式

絲拉克肽 性質(zhì)

儲(chǔ)存條件Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
溶解度H2O:1 mg/mL,澄清,無(wú)色
形態(tài)固體
顏色白色至米白色
水溶解性Soluble to 1 mg/ml in water
序列H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Gly-Ala-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe-OH

絲拉克肽 用途與合成方法

類白色粉末,有特臭。儲(chǔ)存溫度:-20℃Adrenocorticotropic Hormone (ACTH) (1-39), human 是一種黑皮質(zhì)素受體 (melanocortin receptor) 激動(dòng)劑。

Melanocortin receptor

Adrenocorticotropic Hormone (ACTH) (1-39), human (ACTH 1-39), a member of the melanocortin family, stimulates production of CS by the adrenals, but melanocortin receptors are also found in the central nervous system (CNS) and on immune cells. ACTH 1-39 protects neurons in vitro from several apoptotic, excitotoxic and inflammation-related insults. The conditioned medium (CM) is prepared from untreated astroglia (AS) cultures and from AS cultures treated with 200 nM ACTH 1-39 for 24 h, washed to remove ACTH 1-39, then incubated for another 24 h in DMEM. In initial experiments, no difference is found in oligodendroglia (OL) viability in the presence of OL definedmediumwith 2% newborn calf serum (NCS) or AS CM (prepared in DMEM with no serum). After 24 h, OL death under each condition varies between 1 and 4%. Similar results for OL viability are obtained with microglia (MG) CM. In subsequent experiments, controls in each experiment consist of OL in defined medium with 2% NCS.

參考質(zhì)量標(biāo)準(zhǔn)
外觀?白色粉末純度(HPLC) ≥95.0%
醋酸根含量5.0%~12.0%
水分含量≤8.0%
肽含量≥80.0%
用途 
可用于生產(chǎn)促腎上腺皮質(zhì)激素(ACTH),助應(yīng)素。在獸藥生產(chǎn)上,可用于促黃體激素和促卵泡激素的生產(chǎn)。

安全信息

危險(xiǎn)品標(biāo)志Xn
危險(xiǎn)類別碼20/21/22-40
安全說(shuō)明22-36
WGK Germany3
RTECS號(hào)GM7900000
F8-10

MSDS信息

提供商 語(yǔ)言
英文
更新日期產(chǎn)品編號(hào)產(chǎn)品名稱CAS號(hào)包裝價(jià)格
2025/02/05HY-P1211絲拉克肽
Adrenocorticotropic Hormone (ACTH) (1-39), human
12279-41-31mg680元
2025/02/05HY-P1211絲拉克肽
Adrenocorticotropic Hormone (ACTH) (1-39), human
12279-41-35mg1600元

絲拉克肽 上下游產(chǎn)品信息

"絲拉克肽"相關(guān)產(chǎn)品信息
a-硫辛酸 己烯雌酚 異腈基乙酸甲酯 異氰酸叔丁酯 三(2,2,6,6-四甲基-3,5-庚二酸)銪 三乙酰丙酮鐵 芐異腈 乙酰丙酮鉻鹽 異氰基乙酸乙酯 苯硒酚 對(duì)甲基苯磺酰甲基異腈 1,1,3,3-四甲基丁基異氰 乙酰丙酮銀 乙酰丙酮鈷水合物 異腈基正丁烷 乙二胺氯化鉑 2,2,6,6-四甲基-3,5-庚烷二酸鏑 雙水楊酰胺乙基鈷
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