絲拉克肽
中文名稱 | 絲拉克肽 |
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中文同義詞 | 絲拉克肽;六氟硅酸;促腎上腺皮質(zhì)激素(1-39);絲拉克肽, ≥97% (HPLC);人ACTH (1-39)肽;SERACTIDE、絲拉克肽;促腎上腺皮質(zhì)激素ACTH(1-39);促腎上腺皮質(zhì)激素ACTH(1-39), HUMAN絲拉克肽 |
英文名稱 | Seractide |
英文同義詞 | CORTICOTROPIN (HUMAN);CORTICOTROPHIN;CORTICOTROPIN A;H-SER-TYR-SER-MET-GLU-HIS-PHE-ARG-TRP-GLY-LYS-PRO-VAL-GLY-LYS-LYS-ARG-ARG-PRO-VAL-LYS-VAL-TYR-PRO-ASN-GLY-ALA-GLU-ASP-GLU-SER-ALA-GLU-ALA-PHE-PRO-LEU-GLU-PHE-OH;ACTH (1-39) (huMan) Corticotropin;Adrenocorticotropic Hormone (ACTH) (1-39);Seractide acetate;ACTH (1-39), HUMAN |
CAS號(hào) | 12279-41-3 |
分子式 | C207H308N56O58S1 |
分子量 | 4541.07 |
EINECS號(hào) | 634-154-0 |
相關(guān)類別 | 多肽中間體;細(xì)胞生物學(xué);細(xì)胞信號(hào)和神經(jīng)生物學(xué);多肽系列;原料藥;多肽;Peptide;Melanocortin receptor;生化試劑-蛋白質(zhì);藥物多肽 |
Mol文件 | 12279-41-3.mol |
結(jié)構(gòu)式 | ![]() |
絲拉克肽 性質(zhì)
儲(chǔ)存條件 | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
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溶解度 | H2O:1 mg/mL,澄清,無(wú)色 |
形態(tài) | 固體 |
顏色 | 白色至米白色 |
水溶解性 | Soluble to 1 mg/ml in water |
序列 | H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Gly-Ala-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe-OH |
Melanocortin receptor
Adrenocorticotropic Hormone (ACTH) (1-39), human (ACTH 1-39), a member of the melanocortin family, stimulates production of CS by the adrenals, but melanocortin receptors are also found in the central nervous system (CNS) and on immune cells. ACTH 1-39 protects neurons in vitro from several apoptotic, excitotoxic and inflammation-related insults. The conditioned medium (CM) is prepared from untreated astroglia (AS) cultures and from AS cultures treated with 200 nM ACTH 1-39 for 24 h, washed to remove ACTH 1-39, then incubated for another 24 h in DMEM. In initial experiments, no difference is found in oligodendroglia (OL) viability in the presence of OL definedmediumwith 2% newborn calf serum (NCS) or AS CM (prepared in DMEM with no serum). After 24 h, OL death under each condition varies between 1 and 4%. Similar results for OL viability are obtained with microglia (MG) CM. In subsequent experiments, controls in each experiment consist of OL in defined medium with 2% NCS.
醋酸根含量5.0%~12.0%
水分含量≤8.0%
肽含量≥80.0%
安全信息
危險(xiǎn)品標(biāo)志 | Xn |
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危險(xiǎn)類別碼 | 20/21/22-40 |
安全說(shuō)明 | 22-36 |
WGK Germany | 3 |
RTECS號(hào) | GM7900000 |
F | 8-10 |
提供商 | 語(yǔ)言 |
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英文
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更新日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
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2025/02/05 | HY-P1211 | 絲拉克肽 Adrenocorticotropic Hormone (ACTH) (1-39), human | 12279-41-3 | 1mg | 680元 |
2025/02/05 | HY-P1211 | 絲拉克肽 Adrenocorticotropic Hormone (ACTH) (1-39), human | 12279-41-3 | 5mg | 1600元 |