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| | TRIETHYL 4-PHOSPHONOCROTONATE Basic information |
| | TRIETHYL 4-PHOSPHONOCROTONATE Chemical Properties |
| Boiling point | 135 °C0.4 mm Hg(lit.) | | density | 1.128 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.455(lit.) | | Fp | >230 °F | | form | Liquid | | color | Clear light yellow | | CAS DataBase Reference | 10236-14-3(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-37/39-24/25 | | WGK Germany | 3 | | HazardClass | IRRITANT | | HS Code | 29319090 |
| | TRIETHYL 4-PHOSPHONOCROTONATE Usage And Synthesis |
| Chemical Properties | CLEAR LIGHT YELLOW LIQUID | | Uses | Reactant for:
- Iminodipropionic acid as a leaving group for DNA polymerization by HIV-1 reverse transcriptase
- Stereoselective preparation of C1-C19 fragment of macrolide antibiotic aplyronine A using diastereoselective Nozaki-Hiyama-Kishi coupling reactions
- Orally bioavailable GPR40 agonist synthesis
- Synthesis of fluoroketone inhibitors of group VIA calcium-independent phospholipase A2
- Preaparation of mGlu4R agonists
- Dearomatizing cyclization of nicotinyl-substituted esters and ketones
| | Uses | Triethyl 4-phosphonocrotonate is used as a reactant for iminodipropionic acid as a leaving group for DNA polymerization by HIV-1 reverse transcriptase, orally bioavailable GPR40 agonist synthesis, preparation of mGlu4R agonists and synthesis of fluoroketone inhibitors of group VIA calcium-independent phospholipase A2. | | reaction suitability | reaction type: C-C Bond Formation |
| | TRIETHYL 4-PHOSPHONOCROTONATE Preparation Products And Raw materials |
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