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Antibiotics anticancer drugs

Antibiotics Anticancer drugs is a class of antibiotics on killing tumor cells, is a cell cycle non-specific drugs. According to the mechanism of action it can be divided into two categories:
1. the drug cross-links with DNA directly, destroying the structure and function of DNA and preventing DNA replication, such as mitomycin, bleomycin and so on.
2. The drug embeds DNA, interfering template function and inhibiting RNA synthesis, such as actinomycin D, daunomycin, and doxorubicin and so on.
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Structure Chemical Name CAS MF
Doxorubicin hydrochloride Doxorubicin hydrochloride 25316-40-9 C27H29NO11.ClH
Daunorubicin hydrochloride Daunorubicin hydrochloride 23541-50-6 C27H29NO10.ClH
Valrubicin Valrubicin 56124-62-0 C34H36F3NO13
Bleomycin sulfate Bleomycin sulfate 9041-93-4 C110H168N34O46S7
Mitomycin C Mitomycin C 50-07-7 C15H18N4O5
Actinomycin D Actinomycin D 50-76-0 C62H86N12O16
Adriamycin Adriamycin 23214-92-8 C27H29NO11
Epirubicin hydrochloride Epirubicin hydrochloride 56390-09-1 C27H30ClNO11
Idarubicin hydrochloride Idarubicin hydrochloride 57852-57-0 C26H28ClNO9
Pirarubicin Pirarubicin 72496-41-4 C32H37NO12
Epirubicin Epirubicin 56420-45-2 C27H29NO11
Daunorubicin Daunorubicin 20830-81-3 C27H29NO10
Idarubicin Idarubicin 58957-92-9 C26H27NO9
MITHRAMYCIN A MITHRAMYCIN A 18378-89-7 C52H76O24
Bleomycin hydrochloride Bleomycin hydrochloride 67763-87-5 C50H71N16O21S2R.x(HCl)
BLEOMYCIN A5 HYDROCHLORIDE BLEOMYCIN A5 HYDROCHLORIDE 55658-47-4 C57H90ClN19O21S2
ACLARUBICIN HYDROCHLORIDE ACLARUBICIN HYDROCHLORIDE 75443-99-1 C42H54ClNO15
CHROMOMYCIN A3 CHROMOMYCIN A3 7059-24-7 C57H82O26
Streptonigrin Streptonigrin 3930-19-6 C25H22N4O8
Diazomycin B Diazomycin B 7644-67-9 C17H23N7O8
PEPLOMYCIN PEPLOMYCIN 68247-85-8 C61H88N18O21S2
Aclarubicin Aclarubicin 57576-44-0 C42H53NO15
Bleomycin A5 Bleomycin A5 11116-32-8 C57H89N19O21S2
DAUNOMYCINOL DAUNOMYCINOL 28008-55-1 C27H31NO10
ACTINOMYCIN C ACTINOMYCIN C 8052-16-2
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