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66-22-8 Basic information More..
Product Name:Uracil
Synonyms:2-Hydroxy-4(3H)-pyrimidinone;4-Hydroxy-2(1H)-pyrimidinone;Hybar X;hybarx;Pirod;Pyrod;RU 12709;Urasil
CAS:66-22-8
MF:C4H4N2O2
MW:112.09
EINECS:200-621-9
Mol File:66-22-8.mol
66-22-8

Use

Uracil is an organic alkali, and is one of the four major bases in RNA. UTP is the precursor form of uracil in RNA biosynthesis. UTP also acts as a coenzyme to be involved in the biosynthesis of certain sugars. Uracil can block the degradation effect of tegafur, and thus increasing the concentration of fluorouracil which enhance the anti-cancer effects. Fluorouracil has similar clinical indications as uracil. It is mainly used for treating digestive cancer, breast cancer and thyroid cancer. Combination with mitomycin has a good efficacy on treating advanced gastric cancer. Laboratory synthesizes uracil through the cyclization reaction between ethyl malonyl and urea for pharmaceutical and biochemical research.

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  • 2025-05-12
  • CAS:66-22-8
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