10Z-ヒメニアルジシン
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- ￥75400 - ￥95000
- 化學(xué)名: 10Z-ヒメニアルジシン
- 英語名: 10Z-HYMENIALDISINE
- 別名:10Z-ヒメニアルジシン;2-ブロモ-4-[(Z)-2-アミノ-1,5-ジヒドロ-5-オキソ-4H-イミダゾール-4-イリデン]-1,4,5,6,7,8-ヘキサヒドロピロロ[2,3-c]アゼピン-8-オン;2-アミノ-4-[(4Z)-2-ブロモ-8-オキソ-1H,4H,5H,6H,7H,8H-ピロロ[2,3-c]アゼピン-4-イリデン]-4,5-ジヒドロ-1H-イミダゾール-5-オン;ヒメニアルジシン;(Z)-ヒメニアルジシン;(4Z)-2-ブロモ-4-[(2-アミノ-1,5-ジヒドロ-5-オキソ-4H-イミダゾール)-4-イリデン]-4,5,6,7-テトラヒドロピロロ[2,3-c]アゼピン-8(1H)-オン
- CAS番號: 82005-12-7
- 分子式: C11H10BrN5O2
- 分子量: 324.13
- EINECS:
- MDL Number:MFCD04037007
10物価
選択條件：
ブランド
- 富士フイルム和光純薬株式會社(wako)
- Sigma-Aldrich Japan
パッケージ
- 100μG
- 500μg
- 生産者富士フイルム和光純薬株式會社(wako)
- 製品番號W01TOC1532
- 製品説明10Z-ヒメニアルジシン
- 英語製品説明10Z-Hymenialdisine
- 包裝単位500μg
- 価格￥95000
- 更新しました2018-12-26
- 購入
- 生産者Sigma-Aldrich Japan
- 製品番號SAB1411884
- 製品説明 clone 3F9, purified immunoglobulin, buffered aqueous solution
- 英語製品説明ANTI-HD antibody produced in mouse clone 3F9, purified immunoglobulin, buffered aqueous solution
- 包裝単位100μG
- 価格￥78600
- 更新しました2024-03-01
- 購入
- 生産者Sigma-Aldrich Japan
- 製品番號SAB1411856
- 製品説明 clone 1H6, purified immunoglobulin, buffered aqueous solution
- 英語製品説明ANTI-HD antibody produced in mouse clone 1H6, purified immunoglobulin, buffered aqueous solution
- 包裝単位100μG
- 価格￥78600
- 更新しました2024-03-01
- 購入
- 生産者Sigma-Aldrich Japan
- 製品番號SAB1411874
- 製品説明 clone 1A12, purified immunoglobulin, buffered aqueous solution
- 英語製品説明ANTI-HD antibody produced in mouse clone 1A12, purified immunoglobulin, buffered aqueous solution
- 包裝単位100μG
- 価格￥78600
- 更新しました2024-03-01
- 購入
- 生産者Sigma-Aldrich Japan
- 製品番號SAB1411793
- 製品説明 clone 3D6, purified immunoglobulin, buffered aqueous solution
- 英語製品説明ANTI-HD antibody produced in mouse clone 3D6, purified immunoglobulin, buffered aqueous solution
- 包裝単位100μG
- 価格￥78600
- 更新しました2024-03-01
- 購入
- 生産者Sigma-Aldrich Japan
- 製品番號SAB1411855
- 製品説明 clone 4G6, purified immunoglobulin, buffered aqueous solution
- 英語製品説明ANTI-HD antibody produced in mouse clone 4G6, purified immunoglobulin, buffered aqueous solution
- 包裝単位100μG
- 価格￥78600
- 更新しました2024-03-01
- 購入
- 生産者Sigma-Aldrich Japan
- 製品番號SAB1411875
- 製品説明 clone 4F11, purified immunoglobulin, buffered aqueous solution
- 英語製品説明ANTI-HD antibody produced in mouse clone 4F11, purified immunoglobulin, buffered aqueous solution
- 包裝単位100μG
- 価格￥75400
- 更新しました2023-06-01
- 購入
- 生産者Sigma-Aldrich Japan
- 製品番號SAB1411873
- 製品説明 clone 2A7, purified immunoglobulin, buffered aqueous solution
- 英語製品説明ANTI-HD antibody produced in mouse clone 2A7, purified immunoglobulin, buffered aqueous solution
- 包裝単位100μG
- 価格￥75400
- 更新しました2023-06-01
- 購入
- 生産者Sigma-Aldrich Japan
- 製品番號SAB1411876
- 製品説明 clone 1D1, purified immunoglobulin, buffered aqueous solution
- 英語製品説明ANTI-HD antibody produced in mouse clone 1D1, purified immunoglobulin, buffered aqueous solution
- 包裝単位100μG
- 価格￥75400
- 更新しました2023-06-01
- 購入
- 生産者Sigma-Aldrich Japan
- 製品番號SAB1411877
- 製品説明 clone 1C10, purified immunoglobulin, buffered aqueous solution
- 英語製品説明ANTI-HD antibody produced in mouse clone 1C10, purified immunoglobulin, buffered aqueous solution
- 包裝単位100μG
- 価格￥75400
- 更新しました2023-06-01
- 購入
| 生産者 | 製品番號 | 製品説明 | 包裝単位 | 価格 | 更新時間 | 購入 |
|---|---|---|---|---|---|---|
| 富士フイルム和光純薬株式會社(wako) | W01TOC1532 | 10Z-ヒメニアルジシン 10Z-Hymenialdisine |
500μg | ￥95000 | 2018-12-26 | 購入 |
| Sigma-Aldrich Japan | SAB1411884 | clone 3F9, purified immunoglobulin, buffered aqueous solution ANTI-HD antibody produced in mouse clone 3F9, purified immunoglobulin, buffered aqueous solution |
100μG | ￥78600 | 2024-03-01 | 購入 |
| Sigma-Aldrich Japan | SAB1411856 | clone 1H6, purified immunoglobulin, buffered aqueous solution ANTI-HD antibody produced in mouse clone 1H6, purified immunoglobulin, buffered aqueous solution |
100μG | ￥78600 | 2024-03-01 | 購入 |
| Sigma-Aldrich Japan | SAB1411874 | clone 1A12, purified immunoglobulin, buffered aqueous solution ANTI-HD antibody produced in mouse clone 1A12, purified immunoglobulin, buffered aqueous solution |
100μG | ￥78600 | 2024-03-01 | 購入 |
| Sigma-Aldrich Japan | SAB1411793 | clone 3D6, purified immunoglobulin, buffered aqueous solution ANTI-HD antibody produced in mouse clone 3D6, purified immunoglobulin, buffered aqueous solution |
100μG | ￥78600 | 2024-03-01 | 購入 |
| Sigma-Aldrich Japan | SAB1411855 | clone 4G6, purified immunoglobulin, buffered aqueous solution ANTI-HD antibody produced in mouse clone 4G6, purified immunoglobulin, buffered aqueous solution |
100μG | ￥78600 | 2024-03-01 | 購入 |
| Sigma-Aldrich Japan | SAB1411875 | clone 4F11, purified immunoglobulin, buffered aqueous solution ANTI-HD antibody produced in mouse clone 4F11, purified immunoglobulin, buffered aqueous solution |
100μG | ￥75400 | 2023-06-01 | 購入 |
| Sigma-Aldrich Japan | SAB1411873 | clone 2A7, purified immunoglobulin, buffered aqueous solution ANTI-HD antibody produced in mouse clone 2A7, purified immunoglobulin, buffered aqueous solution |
100μG | ￥75400 | 2023-06-01 | 購入 |
| Sigma-Aldrich Japan | SAB1411876 | clone 1D1, purified immunoglobulin, buffered aqueous solution ANTI-HD antibody produced in mouse clone 1D1, purified immunoglobulin, buffered aqueous solution |
100μG | ￥75400 | 2023-06-01 | 購入 |
| Sigma-Aldrich Japan | SAB1411877 | clone 1C10, purified immunoglobulin, buffered aqueous solution ANTI-HD antibody produced in mouse clone 1C10, purified immunoglobulin, buffered aqueous solution |
100μG | ￥75400 | 2023-06-01 | 購入 |
プロパティ
比重(密度) :2.20±0.1 g/cm3(Predicted)
貯蔵溫度 :-20°C
溶解性 :Soluble to 10 mM in DMSO
酸解離定數(shù)(Pka) :9.86±0.20(Predicted)
外見 :Yellow oil.
色 :White to light yellow
貯蔵溫度 :-20°C
溶解性 :Soluble to 10 mM in DMSO
酸解離定數(shù)(Pka) :9.86±0.20(Predicted)
外見 :Yellow oil.
色 :White to light yellow
安全情報
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説明
10Z-Hymenialdisine is a natural marine sponge alkaloid with numerous cellular actions. Most notably, it blocks signaling through the Raf-1/MEK-1/MAPK pathway by potently inhibiting MEK-1 (IC50 = 9 nM). Hymenialdisine also inhibits numerous kinases in vitro, most notably GSK3β, CDK1/cyclin B, CDK5/p25, CK1, and CDK2/cyclin E (IC50s = 10, 22, 28, 35, and 40 nM, respectively), as well as, less potently, ERK1/2 and several isoforms of PKC. Early studies demonstrated that it suppresses inflammatory gene expression by blocking signaling through NF-κB at micromolar concentrations. At similar concentrations, hymenialdisine also blocks bacterial quorum sensing.関連商品価格
- 10Z-ヒメニアルジシン
￥75400-95000 - 5-ブロモ-1H-ピロール-2-カルボキサミド
￥408100-1160600 - 2,4,7,9-テトラメチル-5-デシン-4,7-ジオール
￥2000-47500