PLERIXAFOR
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- $19 - $15400
- Product name: PLERIXAFOR
- CAS: 110078-46-1
- MF: C28H54N8
- MW: 502.78
- EINECS:1592732-453-0
- MDL Number:MFCD05662218
- Synonyms:1,1'-[1,4-Phenylenebis(methylene)]bis-1,4,8,11-tetraazacyclotetradecane;1,4,8,11-Tetraazacyclotetradecane, 1,1'-(1,4-phenylenebis(methylene))bis-;Mozobil;Sdz sid 791;Unii-S915p5499n;1-[[4-(1,4,8,11-tetrazacyclotetradec-1-ylmethyl)phenyl]methyl]-1,4,8,11-tetrazacyclotetradecane;Plerixafor(AMD3100);1-{[4-(1,4,8,11-tetraazacyclotetradecan-1-ylMethyl)phenyl]Methyl}-1,4,8,11-tetraazacyclotetradecane
49 prices
Selected condition：
Brand
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Biosynth Carbosynth
- Chemenu
- Chem-Impex
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- TCI Chemical
- TRC
- Usbiological
Package
- 10mM(in 1mL Ethanol)
- 5mg
- 10mg
- 20mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- 5g
- ManufacturerAmbeed
- Product numberA195007
- Product description1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene 99+%
- Packaging5mg
- Price$19
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA195007
- Product description1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene 99+%
- Packaging10mg
- Price$25
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA195007
- Product description1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene 99+%
- Packaging50mg
- Price$43
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA195007
- Product description1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene 99+%
- Packaging100mg
- Price$68
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA195007
- Product description1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene 99+%
- Packaging250mg
- Price$164
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA195007
- Product description1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene 99+%
- Packaging1g
- Price$420
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA195007
- Product description1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene 99+%
- Packaging5g
- Price$1394
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0009667
- Product descriptionPLERIXAFOR 95.00%
- Packaging10MG
- Price$510
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0009667
- Product descriptionPLERIXAFOR 95.00%
- Packaging250MG
- Price$1375
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0009667
- Product descriptionPLERIXAFOR 95.00%
- Packaging1G
- Price$15400
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA2025
- Product descriptionPlerixafor(AMD3100)
- Packaging10mM(in 1mL Ethanol)
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA2025
- Product descriptionPlerixafor(AMD3100)
- Packaging25mg
- Price$105
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA2025
- Product descriptionPlerixafor(AMD3100)
- Packaging50mg
- Price$188
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA2025
- Product descriptionPlerixafor(AMD3100)
- Packaging100mg
- Price$366
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS022110
- Product description1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene ≥99%
- Packaging5mg
- Price$19
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS022110
- Product description1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene ≥99%
- Packaging10mg
- Price$25
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Ambeed | A195007 | 1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene 99+% | 5mg | $19 | 2021-12-16 | Buy |
| Ambeed | A195007 | 1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene 99+% | 10mg | $25 | 2021-12-16 | Buy |
| Ambeed | A195007 | 1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene 99+% | 50mg | $43 | 2021-12-16 | Buy |
| Ambeed | A195007 | 1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene 99+% | 100mg | $68 | 2021-12-16 | Buy |
| Ambeed | A195007 | 1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene 99+% | 250mg | $164 | 2021-12-16 | Buy |
| Ambeed | A195007 | 1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene 99+% | 1g | $420 | 2021-12-16 | Buy |
| Ambeed | A195007 | 1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene 99+% | 5g | $1394 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0009667 | PLERIXAFOR 95.00% | 10MG | $510 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0009667 | PLERIXAFOR 95.00% | 250MG | $1375 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0009667 | PLERIXAFOR 95.00% | 1G | $15400 | 2021-12-16 | Buy |
| ApexBio Technology | A2025 | Plerixafor(AMD3100) | 10mM(in 1mL Ethanol) | $50 | 2021-12-16 | Buy |
| ApexBio Technology | A2025 | Plerixafor(AMD3100) | 25mg | $105 | 2021-12-16 | Buy |
| ApexBio Technology | A2025 | Plerixafor(AMD3100) | 50mg | $188 | 2021-12-16 | Buy |
| ApexBio Technology | A2025 | Plerixafor(AMD3100) | 100mg | $366 | 2021-12-16 | Buy |
| Arctom | AS022110 | 1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene ≥99% | 5mg | $19 | 2021-12-16 | Buy |
| Arctom | AS022110 | 1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene ≥99% | 10mg | $25 | 2021-12-16 | Buy |
Properties
Melting point :122-125°C
Boiling point :657.5±55.0 °C(Predicted)
Density :0.962
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :Methanol (Slightly), Water (Slightly)
form :Solid
pka :10.60±0.20(Predicted)
color :White to Pale Beige
Stability :Hygroscopic
CAS DataBase Reference :110078-46-1
Boiling point :657.5±55.0 °C(Predicted)
Density :0.962
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :Methanol (Slightly), Water (Slightly)
form :Solid
pka :10.60±0.20(Predicted)
color :White to Pale Beige
Stability :Hygroscopic
CAS DataBase Reference :110078-46-1
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
Autologous hematopoietic stem cell (HSC) transplantation, a standard treatment for hematological malignancies, such as non-Hodgkin’s lymphoma or multiple myeloma, involves collection of HSCs from the patient, chemo- or radiotherapy of the patient to eliminate malignant cells, and retransplantation of the stored HSCs.Plerixafor is a potent antagonist of the CXCR4 chemokine receptor and a first-in-class drug for stem cell mobilization. CXCR4 is specific for stromal-derived-factor-1 (SDF-1), a molecule endowed with potent chemotactic activity forlymphocytes. Because the interaction between SDF-1 and CXCR4 plays an important role in holding HSCs in the bone marrow, drugs that block the activity of CXCR4 receptor are capable of mobilizing HSCs into the bloodstream. In vitro, plerixafor potently blocks SDF-1 binding of CXCR4 and inhibits SDF-1-induced calcium flux (IC50 = 0.01-0.13 mg/mL) and chemotaxis (IC50 = 0.13 mg/mL) in several different cell types. Plerixafor, in combination with G-CSF, is specifically indicated to mobilize HSCs to the peripheral blood for collection and subsequent autologous transplantation in patients with non-Hodgkin’s lymphoma and multiple myeloma.
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