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ChemicalBook >> CAS DataBase List >> PAC1

PAC1

PAC1 price.
  • $55 - $2245.7
  • Product name: PAC1
  • CAS: 315183-21-2
  • MF: C23H28N4O2
  • MW: 392.49
  • EINECS:
  • MDL Number:MFCD03302441
  • Synonyms:PAC1;4-(Phenylmethyl)-1-piperazineaceticacid[[2-hydroxy-3-(2-propenyl)phenyl]methylene]hydrazide;PAC1,4-(PhenylMethyl)-1-piperazineaceticacid[[2-hydroxy-3-(2-propenyl)phenyl]Methylene]hydrazide;4-(Phenylmethyl)-1-piperazineacetic acid 2-[[2-hydroxy-3-(2-propen-1-yl)phenyl]methylene]hydrazide;PAC-1,PAC1;Procaspase activating coMpound 1;(E)-N'-(3-allyl-2-hydroxybenzylidene)-2-(4-benzylpiperazin-1-yl)acetohydrazide;4-(Phenylmethyl)-1-piperazineacetic acid 2-[[2-hydroxy-3-(2-propen-1-yl)phenyl]methylene]hydrazide PAC-1
28 prices
Selected condition：
Brand
  • AK Scientific
  • ApexBio Technology
  • Ark Pharm
  • Axon Medchem
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • DC Chemicals
  • Labseeker
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10μg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 10
  • 50
  • 100mg
  • 250mg
  • 10mM(in 1mL DMSO)
  • 1000mg
  • 1g
  • 2g
  • 10g
  • 400μL
  • ManufacturerAK Scientific
  • Product numberX5905
  • Product descriptionProcaspase-3Activator
  • Packaging50mg
  • Price$165
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberX5905
  • Product descriptionProcaspase-3Activator
  • Packaging250mg
  • Price$696
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8177
  • Product descriptionPAC-1
  • Packaging10mM(in 1mL DMSO)
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberP000572402
  • Product descriptionPAC-1 98+%
  • Packaging50mg
  • Price$204
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberP000572402
  • Product descriptionPAC-1 98+%
  • Packaging10mg
  • Price$73
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1743
  • Product descriptionPAC1-Procaspaseactivatingcompound1 100%
  • Packaging10mg
  • Price$88
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb546139
  • Product descriptionPAC-1 >98%
  • Packaging5mg
  • Price$119
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb546139
  • Product descriptionPAC-1 >98%
  • Packaging25mg
  • Price$217.6
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181301
  • Product descriptionpac-1 >98%
  • Packaging1000mg
  • Price$2245.7
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181301
  • Product descriptionpac-1 >98%
  • Packaging250mg
  • Price$1356.6
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb530400
  • Product descriptionADCYAP1R1
  • Packaging10μg
  • Price$816
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181301
  • Product descriptionpac-1 >98%
  • Packaging100mg
  • Price$690.2
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10009317
  • Product descriptionPAC-1 ≥98%
  • Packaging25mg
  • Price$108
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10009317
  • Product descriptionPAC-1 ≥98%
  • Packaging50mg
  • Price$201
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10009317
  • Product descriptionPAC-1 ≥98%
  • Packaging100mg
  • Price$381
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10009317
  • Product descriptionPAC-1 ≥98%
  • Packaging250mg
  • Price$845
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific X5905 Procaspase-3Activator 50mg $165 2021-12-16 Buy
AK Scientific X5905 Procaspase-3Activator 250mg $696 2021-12-16 Buy
ApexBio Technology A8177 PAC-1 10mM(in 1mL DMSO) $55 2021-12-16 Buy
Ark Pharm P000572402 PAC-1 98+% 50mg $204 2021-12-16 Buy
Ark Pharm P000572402 PAC-1 98+% 10mg $73 2021-12-16 Buy
Axon Medchem Axon1743 PAC1-Procaspaseactivatingcompound1 100% 10mg $88 2021-12-16 Buy
Biorbyt Ltd orb546139 PAC-1 >98% 5mg $119 2021-12-16 Buy
Biorbyt Ltd orb546139 PAC-1 >98% 25mg $217.6 2021-12-16 Buy
Biorbyt Ltd orb181301 pac-1 >98% 1000mg $2245.7 2021-12-16 Buy
Biorbyt Ltd orb181301 pac-1 >98% 250mg $1356.6 2021-12-16 Buy
Biorbyt Ltd orb530400 ADCYAP1R1 10μg $816 2021-12-16 Buy
Biorbyt Ltd orb181301 pac-1 >98% 100mg $690.2 2021-12-16 Buy
Cayman Chemical 10009317 PAC-1 ≥98% 25mg $108 2024-03-01 Buy
Cayman Chemical 10009317 PAC-1 ≥98% 50mg $201 2024-03-01 Buy
Cayman Chemical 10009317 PAC-1 ≥98% 100mg $381 2024-03-01 Buy
Cayman Chemical 10009317 PAC-1 ≥98% 250mg $845 2024-03-01 Buy

Properties

Density :1.14
storage temp. :Store at +4°C
solubility :DMSO: ≥10mg/mL
form :solid
pka :8.82±0.40(Predicted)
color :white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol must be stored under inert gas at -80°C and will be stable for up to 2 months.

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H400 Very toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P273 Avoid release to the environment.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

PAC 1 is a procaspase-activating compound, which in turn produces caspase-3 (EC50 = 0.22 μM). PAC 1 also activates procaspase-7 in a less efficient manner (EC50 = 4.5 μM). This compound is a proapoptotic, inducing apoptosis in both cancerous and non-cancerous cell lines. The induction of apoptosis is dependent on the concentration of procaspase-3 (IC50 values anre 0.003-1.41 and 5.02=9.98 μM, respectively).

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