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ChemicalBook >> CAS DataBase List >> Obeticholic Acid

Obeticholic Acid

Obeticholic Acid price.
  • $50 - $800
  • Product name: Obeticholic Acid
  • CAS: 459789-99-2
  • MF: C26H44O4
  • MW: 420.63
  • EINECS:810-245-2
  • MDL Number:MFCD16621104
  • Synonyms:6alpha-Ethyl-chenodeoxycholic acid;6-Ecdca;6alph;6-Ethyl-cdca;C15636;6-Ethylchenodeoxycholic acid(Obeticholic Acid);Obeticholic Acid;(3α,5β,6α,7α)-6-ethyl-3,7-dihydroxy-cholan-24-oic acid
18 prices
Selected condition:
Brand
  • Adipogen Life Sciences
  • AK Scientific
  • ApexBio Technology
  • ChemScene
  • DC Chemicals
  • Matrix Scientific
  • Sigma-Aldrich
  • TRC
Package
  • 5mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 500mg
  • 1g
  • 5g
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3560-M025
  • Product description6-ECDCA ≥95%(NMR)
  • Packaging25mg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberY1328
  • Product descriptionINT-747
  • Packaging100mg
  • Price$290
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4888
  • Product descriptionObeticholicAcid
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4888
  • Product descriptionObeticholicAcid
  • Packaging25mg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4888
  • Product descriptionObeticholicAcid
  • Packaging100mg
  • Price$470
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3813
  • Product descriptionObeticholicacid >98.0%
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3813
  • Product descriptionObeticholicacid >98.0%
  • Packaging50mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3813
  • Product descriptionObeticholicacid >98.0%
  • Packaging200mg
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3813
  • Product descriptionObeticholicacid >98.0%
  • Packaging500mg
  • Price$650
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7430
  • Product descriptionObeticholicacid(INT-747) >98%
  • Packaging250mg
  • Price$400
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7430
  • Product descriptionObeticholicacid(INT-747) >98%
  • Packaging1g
  • Price$800
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number132791
  • Product description6-Ethylchenodeoxycholic acid 97%
  • Packaging1g
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number132791
  • Product description6-Ethylchenodeoxycholic acid 97%
  • Packaging5g
  • Price$720
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberCDS024140
  • Product description6-Ethylchenodeoxycholic acid
  • Packaging25mg
  • Price$391
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML3096
  • Product descriptionObeticholic acid ≥98% (HPLC)
  • Packaging25MG
  • Price$359
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML3096
  • Product descriptionObeticholic acid ≥98% (HPLC)
  • Packaging5MG
  • Price$89
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CR1-3560-M025 6-ECDCA ≥95%(NMR) 25mg $200 2021-12-16 Buy
AK Scientific Y1328 INT-747 100mg $290 2021-12-16 Buy
ApexBio Technology B4888 ObeticholicAcid 5mg $50 2021-12-16 Buy
ApexBio Technology B4888 ObeticholicAcid 25mg $200 2021-12-16 Buy
ApexBio Technology B4888 ObeticholicAcid 100mg $470 2021-12-16 Buy
ChemScene CS-3813 Obeticholicacid >98.0% 5mg $50 2021-12-16 Buy
ChemScene CS-3813 Obeticholicacid >98.0% 50mg $120 2021-12-16 Buy
ChemScene CS-3813 Obeticholicacid >98.0% 200mg $350 2021-12-16 Buy
ChemScene CS-3813 Obeticholicacid >98.0% 500mg $650 2021-12-16 Buy
DC Chemicals DC7430 Obeticholicacid(INT-747) >98% 250mg $400 2021-12-16 Buy
DC Chemicals DC7430 Obeticholicacid(INT-747) >98% 1g $800 2021-12-16 Buy
Matrix Scientific 132791 6-Ethylchenodeoxycholic acid 97% 1g $450 2021-12-16 Buy
Matrix Scientific 132791 6-Ethylchenodeoxycholic acid 97% 5g $720 2021-12-16 Buy
Sigma-Aldrich CDS024140 6-Ethylchenodeoxycholic acid 25mg $391 2024-03-01 Buy
Sigma-Aldrich SML3096 Obeticholic acid ≥98% (HPLC) 25MG $359 2024-03-01 Buy
Sigma-Aldrich SML3096 Obeticholic acid ≥98% (HPLC) 5MG $89 2024-03-01 Buy

Properties

Melting point :108-110 °C
Boiling point :562.9±25.0 °C(Predicted)
Density :1.091
storage temp. :-20°C
solubility :Soluble in DMSO (up to 35 mg/ml) or in Ethanol (up to 25 mg/ml)
form :White solid.
pka :4.76±0.10(Predicted)
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Obeticholic acid is a potent and selective farnesoid X receptor agonist that promotes the flow of bile in the liver. The drug was approved by the USFDA for the treatment of the rare chronic liver disease primary biliary cholangitis (PBC) in combination with ursodeoxycholic acid (UDCA) in adults with inadequate response to UDCA or as a single agent therapy in adults unable to tolerate UDCA. Obeticholic acid was discovered at the Università de Perugia and developed by Intercept Pharmaceuticals. Obeticholic acid has also been granted orphan drug designation for the treatment of primary sclerosing cholangitis and primary biliary cirrhosis and has received breakthrough therapy designation for the treatment of patients with nonalcohol steatohepatitis (NASH) with liver fibrosis.

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