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ChemicalBook >> CAS DataBase List >> NQDI 1

NQDI 1

NQDI 1 price.
  • $32 - $1339
  • Product name: NQDI 1
  • CAS: 175026-96-7
  • MF: C19H13NO4
  • MW: 319.31
  • EINECS:
  • MDL Number:MFCD03265970
  • Synonyms:LESINURAD (RDEA-594) intermediate;2,7-Dihydro-2,7-dioxo-3H-naphtho[1,2,3-de]quinoline-1-carboxylic acid ethyl ester;NDQI 1;NQDI 1;3H-Naphtho[1,2,3-de]quinoline-1-carboxylic acid, 2,7-dihydro-2,7-dioxo-, ethyl ester;CS-1567;NQDI-1（97%）;NQDI-1;NQDI 1;NQDI1
24 prices
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Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Axon Medchem
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Tocris
  • TRC
Package
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  • 25mg
  • 50mg
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  • 5g
  • ManufacturerAK Scientific
  • Product number9994AF
  • Product descriptionEthyl2,7-dioxo-2,7-dihydro-3H-naphtho[1,2,3-de]quinoline-1-carboxylate
  • Packaging5g
  • Price$1315
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001447
  • Product descriptionNQDI-1 95.00%
  • Packaging10MG
  • Price$275.1
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4474
  • Product descriptionNQDI1
  • Packaging5mg
  • Price$113
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4474
  • Product descriptionNQDI1
  • Packaging10mg
  • Price$189
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4474
  • Product descriptionNQDI1
  • Packaging50mg
  • Price$756
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4474
  • Product descriptionNQDI1
  • Packaging100mg
  • Price$1339
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1814
  • Product descriptionNQDI1 99%
  • Packaging2x10mg
  • Price$198
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16226
  • Product descriptionNQDI-1 ≥95%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16226
  • Product descriptionNQDI-1 ≥95%
  • Packaging5mg
  • Price$93
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16226
  • Product descriptionNQDI-1 ≥95%
  • Packaging10mg
  • Price$169
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16226
  • Product descriptionNQDI-1 ≥95%
  • Packaging25mg
  • Price$381
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5290
  • Product descriptionNQDI-1 95.93%
  • Packaging5mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5290
  • Product descriptionNQDI-1 95.93%
  • Packaging10mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5290
  • Product descriptionNQDI-1 95.93%
  • Packaging50mg
  • Price$400
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5290
  • Product descriptionNQDI-1 95.93%
  • Packaging100mg
  • Price$750
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31002967
  • Product descriptionNQDI-1 98+%
  • Packaging50mg
  • Price$492
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 9994AF Ethyl2,7-dioxo-2,7-dihydro-3H-naphtho[1,2,3-de]quinoline-1-carboxylate 5g $1315 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001447 NQDI-1 95.00% 10MG $275.1 2021-12-16 Buy
ApexBio Technology A4474 NQDI1 5mg $113 2021-12-16 Buy
ApexBio Technology A4474 NQDI1 10mg $189 2021-12-16 Buy
ApexBio Technology A4474 NQDI1 50mg $756 2021-12-16 Buy
ApexBio Technology A4474 NQDI1 100mg $1339 2021-12-16 Buy
Axon Medchem Axon1814 NQDI1 99% 2x10mg $198 2021-12-16 Buy
Cayman Chemical 16226 NQDI-1 ≥95% 1mg $32 2024-03-01 Buy
Cayman Chemical 16226 NQDI-1 ≥95% 5mg $93 2024-03-01 Buy
Cayman Chemical 16226 NQDI-1 ≥95% 10mg $169 2024-03-01 Buy
Cayman Chemical 16226 NQDI-1 ≥95% 25mg $381 2024-03-01 Buy
ChemScene CS-5290 NQDI-1 95.93% 5mg $60 2021-12-16 Buy
ChemScene CS-5290 NQDI-1 95.93% 10mg $100 2021-12-16 Buy
ChemScene CS-5290 NQDI-1 95.93% 50mg $400 2021-12-16 Buy
ChemScene CS-5290 NQDI-1 95.93% 100mg $750 2021-12-16 Buy
Crysdot CD31002967 NQDI-1 98+% 50mg $492 2021-12-16 Buy

Properties

Melting point :310 °C (decomp)
Boiling point :581.4±50.0 °C(Predicted)
Density :1.42±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥5mg/mL (warmed to 60° C)
form :powder
pka :10.76±0.40(Predicted)
color :orange
Stability :Stable for 2 years as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Apoptosis signal-regulating kinase 1 (ASK1) is the ubiquitously expressed mitogen-activated protein kinase kinase kinase 5 involved in a wide range of biological functions that are dependent on cell survival or death. NQDI-1 is a specific inhibitor of ASK1 (IC50 = 3 μM; Ki = 500 nM) that demonstrates potent selectivity against various serine/threonine and tyrosine protein kinases. It has been used to promote survival of induced pluripotent stem cell populations and to protect neurons from reactive oxygen species-induced apoptosis in a model of ischemia.

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