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ChemicalBook >> CAS DataBase List >> LY 171883

LY 171883

LY 171883 price.
  • $40 - $1166.67
  • Product name: LY 171883
  • CAS: 88107-10-2
  • MF: C16H22N4O3
  • MW: 318.37
  • EINECS:
  • MDL Number:MFCD00211057
  • Synonyms:TOMELUKAST;LY-171,833;LY 171883;5-[4-4-ACETYL-3-HYDROXY-2-PROPYLPHENOXYBUTYL]-1H-TETRAZOLE;5-[4-(1-ACETYL-2-HYDROXY-3-PROPYLPHENOXY)BUTYL]-1H-TETRAZOLE;1-[2-HYDROXY-3-PROPYL-4-[4-(1H-TETRAZOL-5-YL)BUTOXY]PHENYL]ETHANONE;1-(2-hydroxy-3-propyl-4-(4-(1h-tetrazol-5-yl)butoxy)phenyl)-ethanon ;2’-hydroxy-3’-propyl-4-(4-(1h-tetrazol-5-yl)butoxy)-acetophenon
14 prices
Selected condition:
Brand
  • AK Scientific
  • Alfa Aesar
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • TRC
Package
  • 5mg
  • 10mg
  • 25mg
  • 50MG
  • 100MG
  • ManufacturerAK Scientific
  • Product number0123BA
  • Product descriptionTomelukast
  • Packaging5mg
  • Price$143
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ67028
  • Product descriptionLY 171883, 98%
  • Packaging10mg
  • Price$165
  • Updated2023-06-20
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0004450
  • Product description5-[4-(1-ACETYL-2-HYDROXY-3-PROPYLPHENOXY)BUTYL]-1H-TETRAZOLE 95.00%
  • Packaging100MG
  • Price$1166.67
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0004450
  • Product description5-[4-(1-ACETYL-2-HYDROXY-3-PROPYLPHENOXY)BUTYL]-1H-TETRAZOLE 95.00%
  • Packaging50MG
  • Price$856.2
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0004450
  • Product description5-[4-(1-ACETYL-2-HYDROXY-3-PROPYLPHENOXY)BUTYL]-1H-TETRAZOLE 95.00%
  • Packaging5MG
  • Price$151.8
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3110
  • Product descriptionLY171883
  • Packaging10mg
  • Price$84
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3110
  • Product descriptionLY171883
  • Packaging50mg
  • Price$355
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3110
  • Product descriptionLY171883
  • Packaging100mg
  • Price$622
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number70710
  • Product descriptionLY171883 ≥98%
  • Packaging5mg
  • Price$40
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number70710
  • Product descriptionLY171883 ≥98%
  • Packaging10mg
  • Price$76
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number70710
  • Product descriptionLY171883 ≥98%
  • Packaging50mg
  • Price$312
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number70710
  • Product descriptionLY171883 ≥98%
  • Packaging100mg
  • Price$545
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberL503123
  • Product descriptionLY171883
  • Packaging10mg
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberL503123
  • Product descriptionLY171883
  • Packaging25mg
  • Price$130
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 0123BA Tomelukast 5mg $143 2021-12-16 Buy
Alfa Aesar J67028 LY 171883, 98% 10mg $165 2023-06-20 Buy
American Custom Chemicals Corporation API0004450 5-[4-(1-ACETYL-2-HYDROXY-3-PROPYLPHENOXY)BUTYL]-1H-TETRAZOLE 95.00% 100MG $1166.67 2021-12-16 Buy
American Custom Chemicals Corporation API0004450 5-[4-(1-ACETYL-2-HYDROXY-3-PROPYLPHENOXY)BUTYL]-1H-TETRAZOLE 95.00% 50MG $856.2 2021-12-16 Buy
American Custom Chemicals Corporation API0004450 5-[4-(1-ACETYL-2-HYDROXY-3-PROPYLPHENOXY)BUTYL]-1H-TETRAZOLE 95.00% 5MG $151.8 2021-12-16 Buy
ApexBio Technology C3110 LY171883 10mg $84 2021-12-16 Buy
ApexBio Technology C3110 LY171883 50mg $355 2021-12-16 Buy
ApexBio Technology C3110 LY171883 100mg $622 2021-12-16 Buy
Cayman Chemical 70710 LY171883 ≥98% 5mg $40 2024-03-01 Buy
Cayman Chemical 70710 LY171883 ≥98% 10mg $76 2024-03-01 Buy
Cayman Chemical 70710 LY171883 ≥98% 50mg $312 2024-03-01 Buy
Cayman Chemical 70710 LY171883 ≥98% 100mg $545 2024-03-01 Buy
TRC L503123 LY171883 10mg $65 2021-12-16 Buy
TRC L503123 LY171883 25mg $130 2021-12-16 Buy

Properties

Melting point :117-119℃
Boiling point :553.0±60.0 °C(Predicted)
Density :1.220±0.06 g/cm3(Predicted)
storage temp. :Store at +4°C
solubility :Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 15 mg/ml),
form :White solid.
pka :5.02±0.10(Predicted)
color :White
Stability :Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months
CAS DataBase Reference :88107-10-2

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P330 Rinse mouth.

Description

LY171883 is a selective, potent, orally active antagonist of the leukotriene D4 receptor. Dissociation constants (KB) for LY171883 on guinea pig ileum and parenchyma are 0.07 and 0.34 μM, respectively. LY171883 is an inhibitor of phosphodiesterase obtained from human polymorphonuclear leukocytes (IC50 of 22.6 μM) and various guinea pig tissues (IC50s range from 6.9-209 μM). At a concentration of 50-100 μM, LY171883 binds to the PPARγ nuclear receptor, inducing adipogenesis in cultured NIH3T3 fibroblasts.

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