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ChemicalBook >> CAS DataBase List >> HA14-1

HA14-1

HA14-1 price.
  • $25 - $2395.3
  • Product name: HA14-1
  • CAS: 65673-63-4
  • MF: C17H17BrN2O5
  • MW: 409.23
  • EINECS:
  • MDL Number:MFCD00218213
  • Synonyms:2-Amino-6-bromo-alpha-cyano-3-(ethoxycarbonyl)-(4H)-1-benzopyrane-4-aceticacidethylester;ethyl 6-broMo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chroMene-3-carboxylate;2-Amino-6-bromo-α-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic acid ethyl ester, Ethyl [2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)]-4H-chromene-3-carboxylate;[Ethyl 2-amino-6-bromo-4-(1cyano-2-ethoxy-2-oxoethyl)-4H-chromene3-3carboxylate], Ethyl [2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)]-4H-chromene-3-carboxylate;2-Amino-6-bromo-α-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-aceticacidethylester;2-Amino-6-bromo-alpha-cyano-3-(ethoxycarbonyl)-(alphaR,4R)-rel-4H-1-benzopyran-4-acetic acid ethyl ester;Ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-1-benzopyran-3-carboxylate 97%;HA 14-1, Ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate, 2-[2-Amino-6-bromo-3-(ethoxycarbonyl)-4H-chromen-4-yl]-3-ethoxy-3-oxopropanenitrile
33 prices
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Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Apolloscientific
  • Arctom
  • Atlantic Research Chemicals
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • DC Chemicals
  • Matrix Scientific
  • SynQuest Laboratories
  • Tocris
  • TRC
  • Usbiological
Package
  • 5
  • 10mg
  • 25mg
  • 25
  • 5mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 1gm:
  • ManufacturerAK Scientific
  • Product numberY9750
  • Product descriptionEthyl2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate
  • Packaging10mg
  • Price$104
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberY9750
  • Product descriptionEthyl2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate
  • Packaging50mg
  • Price$134
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberY9750
  • Product descriptionEthyl2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate
  • Packaging100mg
  • Price$155
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberY9750
  • Product descriptionEthyl2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate
  • Packaging1g
  • Price$532
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA350244
  • Product descriptionrel-(R)-Ethyl2-amino-6-bromo-4-((R)-1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate(relative) 98+%
  • Packaging10mg
  • Price$38
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA350244
  • Product descriptionrel-(R)-Ethyl2-amino-6-bromo-4-((R)-1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate(relative) 98+%
  • Packaging50mg
  • Price$63
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA350244
  • Product descriptionrel-(R)-Ethyl2-amino-6-bromo-4-((R)-1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate(relative) 98+%
  • Packaging100mg
  • Price$81
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA350244
  • Product descriptionrel-(R)-Ethyl2-amino-6-bromo-4-((R)-1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate(relative) 98+%
  • Packaging250mg
  • Price$155
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA350244
  • Product descriptionrel-(R)-Ethyl2-amino-6-bromo-4-((R)-1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate(relative) 98+%
  • Packaging1g
  • Price$406
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008386
  • Product descriptionHA 14-1 95.00%
  • Packaging250MG
  • Price$247.8
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008386
  • Product descriptionHA 14-1 95.00%
  • Packaging1G
  • Price$896.23
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8168
  • Product descriptionHA 14-1
  • Packaging50mg
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR200014
  • Product descriptionEthyl2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-1-benzopyran-3-carboxylate 95%
  • Packaging250mg
  • Price$134
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR200014
  • Product descriptionEthyl2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-1-benzopyran-3-carboxylate 95%
  • Packaging1g
  • Price$404
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS026351
  • Product descriptionrel-(R)-Ethyl2-amino-6-bromo-4-((R)-1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate(relative)
  • Packaging100mg
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerAtlantic Research Chemicals
  • Product numberES10064
  • Product descriptionEthyl2-Amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate 95%
  • Packaging1gm:
  • Price$261.56
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific Y9750 Ethyl2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate 10mg $104 2021-12-16 Buy
AK Scientific Y9750 Ethyl2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate 50mg $134 2021-12-16 Buy
AK Scientific Y9750 Ethyl2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate 100mg $155 2021-12-16 Buy
AK Scientific Y9750 Ethyl2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate 1g $532 2021-12-16 Buy
Ambeed A350244 rel-(R)-Ethyl2-amino-6-bromo-4-((R)-1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate(relative) 98+% 10mg $38 2021-12-16 Buy
Ambeed A350244 rel-(R)-Ethyl2-amino-6-bromo-4-((R)-1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate(relative) 98+% 50mg $63 2021-12-16 Buy
Ambeed A350244 rel-(R)-Ethyl2-amino-6-bromo-4-((R)-1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate(relative) 98+% 100mg $81 2021-12-16 Buy
Ambeed A350244 rel-(R)-Ethyl2-amino-6-bromo-4-((R)-1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate(relative) 98+% 250mg $155 2021-12-16 Buy
Ambeed A350244 rel-(R)-Ethyl2-amino-6-bromo-4-((R)-1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate(relative) 98+% 1g $406 2021-12-16 Buy
American Custom Chemicals Corporation API0008386 HA 14-1 95.00% 250MG $247.8 2021-12-16 Buy
American Custom Chemicals Corporation API0008386 HA 14-1 95.00% 1G $896.23 2021-12-16 Buy
ApexBio Technology A8168 HA 14-1 50mg $110 2021-12-16 Buy
Apolloscientific OR200014 Ethyl2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-1-benzopyran-3-carboxylate 95% 250mg $134 2021-12-16 Buy
Apolloscientific OR200014 Ethyl2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-1-benzopyran-3-carboxylate 95% 1g $404 2021-12-16 Buy
Arctom AS026351 rel-(R)-Ethyl2-amino-6-bromo-4-((R)-1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate(relative) 100mg $80 2021-12-16 Buy
Atlantic Research Chemicals ES10064 Ethyl2-Amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate 95% 1gm: $261.56 2021-12-16 Buy

Properties

Melting point :105 °C
Density :1.480
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: 26 mg/mL
form :powder
color :White to light yellow
CAS DataBase Reference :65673-63-4

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

HA14-1 is a small, cell-permeable nonpeptidic ligand that binds to the Bcl-2 surface pocket and blocks its biological action. HA14-1 induces apoptosis in HL-60 leukemic cells overexpressing Bcl-2 and in NIH 3T3 cells via the activation of caspases by a mechanism that is distinct from Fas-mediated apoptosis.

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