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ChemicalBook >> CAS DataBase List >> Flutamide

Flutamide

Flutamide price.
  • $6 - $630
  • Product name: Flutamide
  • CAS: 13311-84-7
  • MF: C11H11F3N2O3
  • MW: 276.21
  • EINECS:236-341-9
  • MDL Number:MFCD00072009
  • Synonyms:TIMTEC-BB SBB006930;N1-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]-2-METHYLPROPANAMIDE;2-METHYL-N-(4'-NITRO-3'-(TRIFLUOROMETHYL)PHENYL)PROPANAMIDE;2-METHYL-N-(4-NITRO-3-[TRIFLUOROMETHYL]PHENYL)PROPANAMIDE;FLUTAMIDE;AURORA KA-860;2-Methyl-N-[4-nitro-3-(trifluoromethyl)-phenyl]-propionamide;Flutamide USP25
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  • 10mM(in 1mL DMSO)
  • ManufacturerAHH
  • Product numberMT-51866
  • Product descriptionFlutamide 98%
  • Packaging250g
  • Price$630
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberF006
  • Product descriptionFlutamide
  • Packaging5g
  • Price$14
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberJ10037
  • Product descriptionFlutamide
  • Packaging5g
  • Price$69
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberJ94003
  • Product descriptionFlutamide
  • Packaging500g
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberF006
  • Product descriptionFlutamide
  • Packaging500g
  • Price$401
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ94003
  • Product descriptionFlutamide
  • Packaging1kg
  • Price$500
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA208282
  • Product descriptionN-(4-Nitro-3-(trifluoromethyl)phenyl)isobutyramide 98+%
  • Packaging1g
  • Price$6
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA208282
  • Product descriptionN-(4-Nitro-3-(trifluoromethyl)phenyl)isobutyramide 98+%
  • Packaging5g
  • Price$12
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA208282
  • Product descriptionN-(4-Nitro-3-(trifluoromethyl)phenyl)isobutyramide 98+%
  • Packaging10g
  • Price$20
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA208282
  • Product descriptionN-(4-Nitro-3-(trifluoromethyl)phenyl)isobutyramide 98+%
  • Packaging25g
  • Price$34
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA208282
  • Product descriptionN-(4-Nitro-3-(trifluoromethyl)phenyl)isobutyramide 98+%
  • Packaging100g
  • Price$110
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA208282
  • Product descriptionN-(4-Nitro-3-(trifluoromethyl)phenyl)isobutyramide 98+%
  • Packaging500g
  • Price$397
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1376
  • Product descriptionFlutamide
  • Packaging5g
  • Price$76
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB1376
  • Product descriptionFlutamide
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1376
  • Product descriptionFlutamide
  • Packaging1g
  • Price$42
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1376
  • Product descriptionFlutamide
  • Packaging1unit
  • Price$28
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-51866 Flutamide 98% 250g $630 2021-12-16 Buy
AK Scientific F006 Flutamide 5g $14 2021-12-16 Buy
AK Scientific J10037 Flutamide 5g $69 2021-12-16 Buy
AK Scientific J94003 Flutamide 500g $300 2021-12-16 Buy
AK Scientific F006 Flutamide 500g $401 2021-12-16 Buy
AK Scientific J94003 Flutamide 1kg $500 2021-12-16 Buy
Ambeed A208282 N-(4-Nitro-3-(trifluoromethyl)phenyl)isobutyramide 98+% 1g $6 2021-12-16 Buy
Ambeed A208282 N-(4-Nitro-3-(trifluoromethyl)phenyl)isobutyramide 98+% 5g $12 2021-12-16 Buy
Ambeed A208282 N-(4-Nitro-3-(trifluoromethyl)phenyl)isobutyramide 98+% 10g $20 2021-12-16 Buy
Ambeed A208282 N-(4-Nitro-3-(trifluoromethyl)phenyl)isobutyramide 98+% 25g $34 2021-12-16 Buy
Ambeed A208282 N-(4-Nitro-3-(trifluoromethyl)phenyl)isobutyramide 98+% 100g $110 2021-12-16 Buy
Ambeed A208282 N-(4-Nitro-3-(trifluoromethyl)phenyl)isobutyramide 98+% 500g $397 2021-12-16 Buy
ApexBio Technology B1376 Flutamide 5g $76 2021-12-16 Buy
ApexBio Technology B1376 Flutamide 10mM(in 1mL DMSO) $50 2021-12-16 Buy
ApexBio Technology B1376 Flutamide 1g $42 2021-12-16 Buy
ApexBio Technology B1376 Flutamide 1unit $28 2021-12-16 Buy

Properties

Melting point :112 °C
Boiling point :400.3±45.0 °C(Predicted)
Density :1.3649 (estimate)
storage temp. :2-8°C
solubility :Practically insoluble in water, freely soluble in acetone and in ethanol (96 per cent).
pka :13.12±0.70(Predicted)
form :Solid
color :Pale Yellow to Light Yellow
Merck :14,4208
InChI :InChI=1S/C11H11F3N2O3/c1-6(2)10(17)15-7-3-4-9(16(18)19)8(5-7)11(12,13)14/h3-6H,1-2H3,(H,15,17)
InChIKey :MKXKFYHWDHIYRV-UHFFFAOYSA-N
SMILES :C(NC1=CC=C([N+]([O-])=O)C(C(F)(F)F)=C1)(=O)C(C)C
CAS DataBase Reference :13311-84-7(CAS DataBase Reference)
EPA Substance Registry System :Flutamide (13311-84-7)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
H411 Toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 2
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P273 Avoid release to the environment.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Flutamide is a kind of synthetic, non-steroidal antiandrogen which is mainly used for the treatment of prostate cancer. It is a kind of toluidine derivative and a nonsteroidal antiandrogen with a similar structure of bicalutamide and nilutamide. The mechanism of its anti-cancer property is through acting as a selective antagonist of the androgen receptor (AR), preventing androgens such as testosterone and its active metabolite dihydrotestosterone from binding to ARs in the prostate gland. This process inhibits androgen-dependent DNA and protein synthesis in the tumor cell. Therefore, it can prevent androgens from stimulating the growth of prostate cancer cells. Moreover, it can also be used for the treatment of hyperandrogenism in women. It is quite effective in alleviating symptoms such as acne, seborrhea, hirsutism and androgenetic alopecia. Finally, it is also useful as a component in the transgender hormone therapy.

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