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ChemicalBook >> CAS DataBase List >> BMX-IN-1

BMX-IN-1

BMX-IN-1 price.
  • $32 - $1683
  • Product name: BMX-IN-1
  • CAS: 1431525-23-3
  • MF: C29H24N4O4S
  • MW: 524.59
  • EINECS:
  • MDL Number:MFCD25372042
  • Synonyms:BMX kinase inhibitor;N-(2-Methyl-5-(9-(4-(MethylsulfonaMido)phenyl)-2-oxobenzo[h][1,6]naphthyridin-1(2H)-yl)phenyl)acrylaMide;N-[2-Methyl-5-[9-[4-[(methylsulfonyl)amino]phenyl]-2-oxobenzo[h]-1,6-naphthyridin-1(2H)-yl]phenyl]-2-propenamide;henyl]-;BMX-IN-1;BMX-INQ: What is BMX-IN Q: What is the CAS Number of BMX-IN Q: What is the storage condition of BMX-IN;BMX-IN-1 USP/EP/BP;2-Propenamide, N-[2-methyl-5-[9-[4-[(methylsulfonyl)amino]phenyl]-2-oxobenzo[h]-1,6-naphthyridin-1(2H)-yl]phenyl]-
26 prices
Selected condition:
Brand
  • AK Scientific
  • ApexBio Technology
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
Package
  • 500μg
  • 50mg
  • 100mg
  • 5
  • 10mM(in 1mL DMSO)
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • ManufacturerAK Scientific
  • Product number9414DU
  • Product descriptionBmx-IN-1
  • Packaging1mg
  • Price$164
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number9414DU
  • Product descriptionBmx-IN-1
  • Packaging5mg
  • Price$336
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3260
  • Product descriptionBMX-IN-1
  • Packaging2mg
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3260
  • Product descriptionBMX-IN-1
  • Packaging5mg
  • Price$170
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3260
  • Product descriptionBMX-IN-1
  • Packaging10mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3260
  • Product descriptionBMX-IN-1
  • Packaging10mM(in 1mL DMSO)
  • Price$325
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3260
  • Product descriptionBMX-IN-1
  • Packaging50mg
  • Price$990
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3260
  • Product descriptionBMX-IN-1
  • Packaging100mg
  • Price$1400
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb611765
  • Product descriptionBMX-IN-1
  • Packaging10mg
  • Price$639.2
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb611765
  • Product descriptionBMX-IN-1
  • Packaging50mg
  • Price$1288.6
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb611765
  • Product descriptionBMX-IN-1
  • Packaging100mg
  • Price$1683
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19165
  • Product descriptionBMX-IN-1 ≥95%
  • Packaging500μg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19165
  • Product descriptionBMX-IN-1 ≥95%
  • Packaging1mg
  • Price$61
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19165
  • Product descriptionBMX-IN-1 ≥95%
  • Packaging5mg
  • Price$214
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1295
  • Product descriptionBMX-IN-1 99.04%
  • Packaging2mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1295
  • Product descriptionBMX-IN-1 99.04%
  • Packaging5mg
  • Price$170
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 9414DU Bmx-IN-1 1mg $164 2021-12-16 Buy
AK Scientific 9414DU Bmx-IN-1 5mg $336 2021-12-16 Buy
ApexBio Technology A3260 BMX-IN-1 2mg $95 2021-12-16 Buy
ApexBio Technology A3260 BMX-IN-1 5mg $170 2021-12-16 Buy
ApexBio Technology A3260 BMX-IN-1 10mg $300 2021-12-16 Buy
ApexBio Technology A3260 BMX-IN-1 10mM(in 1mL DMSO) $325 2021-12-16 Buy
ApexBio Technology A3260 BMX-IN-1 50mg $990 2021-12-16 Buy
ApexBio Technology A3260 BMX-IN-1 100mg $1400 2021-12-16 Buy
Biorbyt Ltd orb611765 BMX-IN-1 10mg $639.2 2021-12-16 Buy
Biorbyt Ltd orb611765 BMX-IN-1 50mg $1288.6 2021-12-16 Buy
Biorbyt Ltd orb611765 BMX-IN-1 100mg $1683 2021-12-16 Buy
Cayman Chemical 19165 BMX-IN-1 ≥95% 500μg $32 2024-03-01 Buy
Cayman Chemical 19165 BMX-IN-1 ≥95% 1mg $61 2024-03-01 Buy
Cayman Chemical 19165 BMX-IN-1 ≥95% 5mg $214 2024-03-01 Buy
ChemScene CS-1295 BMX-IN-1 99.04% 2mg $90 2021-12-16 Buy
ChemScene CS-1295 BMX-IN-1 99.04% 5mg $170 2021-12-16 Buy

Properties

Density :1.397±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :insoluble in H2O; insoluble in EtOH; ≥5.25 mg/mL in DMSO
form :solid
pka :7.77±0.10(Predicted)
color :White to yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

BMX-IN-1 is a selective, irreversible inhibitor of bone marrow tyrosine kinase on chromosome X (BMX; IC50 = 8 nM) that targets Cys496 in the BMX ATP binding domain. It additionally targets the related Bruton’s tyrosine kinase (BTK) with an IC50 value of 10.4 nM, but is more than 47-656-fold less potent for inhibition of Blk, JAK3, EGFR, Itk, or Tec activity. BMX-IN-1 was shown to inhibit the proliferation of Tel-BMX-transformed Ba/F3 prostate cancer cells with a GI50 value of 25 nM. Antiproliferative activity was also observed in RV-1, DU-145, PC-3, and VCAP prostate cancer cell lines (GI50s = 2.54, 4.38, 5.37, and 2.46 μM, respectively).