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ChemicalBook >> CAS DataBase List >>BMX-IN-1

BMX-IN-1

CAS No.
1431525-23-3
Chemical Name:
BMX-IN-1
Synonyms
henyl]-;BMX-IN-1;BMX inhibitor 1;BMX-IN-1 USP/EP/BP;BMX kinase inhibitor;BMX-IN-1, 10 mM in DMSO;BMX-IN-1 (BMX kinase inhibitor;6]naphthyridin-1(2H)-yl)phenyl)acrylamide;N-(2-methyl-5-(9-(4-(methylsulfonamido)phenyl)-2-oxobenzo[h][1;inhibit,BMX Kinase,BMX IN 1,Bruton tyrosine kinase,Btk,Inhibitor,BMXIN1
CBNumber:
CB62666602
Molecular Formula:
C29H24N4O4S
Molecular Weight:
524.59
MDL Number:
MFCD25372042
MOL File:
1431525-23-3.mol
Last updated:2025-01-27 09:38:02

BMX-IN-1 Properties

Density 1.397±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility insoluble in H2O; insoluble in EtOH; ≥5.25 mg/mL in DMSO
form solid
pka 7.77±0.10(Predicted)
color White to yellow
UNSPSC Code 12352200
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

BMX-IN-1 price More Price(26)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 5.05021 BMX-IN-1 - CAS 1431525-23-4 - Calbiochem 1431525-23-3 10mg $280 2024-03-01 Buy
Cayman Chemical 19165 BMX-IN-1 ≥95% 1431525-23-3 500μg $32 2024-03-01 Buy
Cayman Chemical 19165 BMX-IN-1 ≥95% 1431525-23-3 1mg $61 2024-03-01 Buy
Cayman Chemical 19165 BMX-IN-1 ≥95% 1431525-23-3 5mg $214 2024-03-01 Buy
Tocris 5123 BMX-IN-1 ≥98%(HPLC) 1431525-23-3 5 $160 2021-12-16 Buy
Product number Packaging Price Buy
5.05021 10mg $280 Buy
19165 500μg $32 Buy
19165 1mg $61 Buy
19165 5mg $214 Buy
5123 5 $160 Buy

BMX-IN-1 Chemical Properties,Uses,Production

Description

BMX-IN-1 is a selective, irreversible inhibitor of bone marrow tyrosine kinase on chromosome X (BMX; IC50 = 8 nM) that targets Cys496 in the BMX ATP binding domain. It additionally targets the related Bruton’s tyrosine kinase (BTK) with an IC50 value of 10.4 nM, but is more than 47-656-fold less potent for inhibition of Blk, JAK3, EGFR, Itk, or Tec activity. BMX-IN-1 was shown to inhibit the proliferation of Tel-BMX-transformed Ba/F3 prostate cancer cells with a GI50 value of 25 nM. Antiproliferative activity was also observed in RV-1, DU-145, PC-3, and VCAP prostate cancer cell lines (GI50s = 2.54, 4.38, 5.37, and 2.46 μM, respectively).

target

BMX Kinase

storage

Store at -20°C

BMX-IN-1 Preparation Products And Raw materials

Raw materials

Preparation Products

BMX-IN-1 Suppliers

Global( 80)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32965 60
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28172 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6312 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250 1026@dideu.com China 22787 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
Nantong HI-FUTURE Biology Co., Ltd. 		+undefined18051384581 sales@chemhifuture.com China 3135 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38631 58
Aladdin Scientific 		tp@aladdinsci.com United States 57505 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58

View Lastest Price from BMX-IN-1 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
BMX-IN-1 pictures 2024-11-18 BMX-IN-1
1431525-23-3
 US $48.00-198.00 / mg ≥98% 10g TargetMol Chemicals Inc.
BMX-IN-1 pictures 2024-11-18 BMX-IN-1
1431525-23-3
 US $48.00-198.00 / mg ≥98% 10g TargetMol Chemicals Inc.
  • BMX-IN-1 pictures
  • BMX-IN-1
    1431525-23-3
  • US $48.00-198.00 / mg
  • ≥98%
  • TargetMol Chemicals Inc.
  • BMX-IN-1 pictures
  • BMX-IN-1
    1431525-23-3
  • US $48.00-198.00 / mg
  • ≥98%
  • TargetMol Chemicals Inc.

BMX-IN-1 Spectrum

BMX kinase inhibitor N-(2-Methyl-5-(9-(4-(MethylsulfonaMido)phenyl)-2-oxobenzo[h][1,6]naphthyridin-1(2H)-yl)phenyl)acrylaMide N-[2-Methyl-5-[9-[4-[(methylsulfonyl)amino]phenyl]-2-oxobenzo[h]-1,6-naphthyridin-1(2H)-yl]phenyl]-2-propenamide henyl]- BMX-IN-1 BMX-INQ: What is BMX-IN Q: What is the CAS Number of BMX-IN Q: What is the storage condition of BMX-IN BMX-IN-1 USP/EP/BP 2-Propenamide, N-[2-methyl-5-[9-[4-[(methylsulfonyl)amino]phenyl]-2-oxobenzo[h]-1,6-naphthyridin-1(2H)-yl]phenyl]- BMX inhibitor 1 BMX-IN-1 (BMX kinase inhibitor N-(2-methyl-5-(9-(4-(methylsulfonamido)phenyl)-2-oxobenzo[h][1 BMX KINASE INHIBITOR;N-(2-METHYL-5-(9-(4-(METHYLSULFONAMIDO)PHENYL)-2-OXOBENZO[H][1;6]NAPHTHYRIDIN-1(2H)-YL)PHENYL)ACRYLAMIDE 6]naphthyridin-1(2H)-yl)phenyl)acrylamide inhibit,BMX Kinase,BMX IN 1,Bruton tyrosine kinase,Btk,Inhibitor,BMXIN1 BMX-IN-1, 10 mM in DMSO 1431525-23-3