Adapalene
|
- $6 - $1504.5
- Product name: Adapalene
- CAS: 106685-40-9
- MF: C28H28O3
- MW: 412.52
- EINECS:620-513-9
- MDL Number:MFCD03106112
- Synonyms:ADAPALENE;6-[3-(1-ADAMANTYL)-4-METHOXYPHENYL]-2-NAPHTHOIC ACID;6-(4-Methoxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)-2-naphthalenecarboxylic Acid;CD-271;Differi;6-[4-Methoxy-3-(adamantan-1-yl)phenyl]-2-naphthalenecarboxylic acid;6-[3-(adaMantan-1-yl)-4-Methoxyphenyl]naphthalene-2-carboxylic acid;[1]6-[4-Methoxy-3-(tricyclo[3.3.1.1~3,7~]dec-1-yl)phenyl]naphthalene-2-carboxylic acid
68 prices
Selected condition：
Brand
- AHH
- AK Scientific
- Alfa Aesar
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- y0001119
- 10mg
- 200MG
- 500mg
- 50
- y0001121
- 2g
- 5g
- 10
- 25mg
- 100mg
- 250mg
- 1g
- 10g
- 50mg
- 0.25G
- 25g
- 10mM(in 1mL DMSO)
- ManufacturerAHH
- Product numberAPI-1690
- Product descriptionAdapalene 98%
- Packaging1g
- Price$610
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberI810
- Product descriptionAdapalene
- Packaging100mg
- Price$39
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ50424
- Product descriptionAdapalene
- Packaging250mg
- Price$45
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberI810
- Product descriptionAdapalene
- Packaging250mg
- Price$61
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ50424
- Product descriptionAdapalene
- Packaging1g
- Price$125
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberI810
- Product descriptionAdapalene
- Packaging1g
- Price$167
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberI810
- Product descriptionAdapalene
- Packaging10g
- Price$667
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ67025
- Product descriptionAdapalene
- Packaging25mg
- Price$117
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ67025
- Product descriptionAdapalene
- Packaging50mg
- Price$144
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA105293
- Product description6-(3-(Adamantan-1-yl)-4-methoxyphenyl)-2-naphthoicacid 99+%
- Packaging50mg
- Price$6
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA105293
- Product description6-(3-(Adamantan-1-yl)-4-methoxyphenyl)-2-naphthoicacid 99+%
- Packaging100mg
- Price$10
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA105293
- Product description6-(3-(Adamantan-1-yl)-4-methoxyphenyl)-2-naphthoicacid 99+%
- Packaging250mg
- Price$13
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA105293
- Product description6-(3-(Adamantan-1-yl)-4-methoxyphenyl)-2-naphthoicacid 99+%
- Packaging1g
- Price$13
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA105293
- Product description6-(3-(Adamantan-1-yl)-4-methoxyphenyl)-2-naphthoicacid 99+%
- Packaging25g
- Price$441
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0001385
- Product descriptionAdapalene 95.00%
- Packaging0.25G
- Price$407
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1267
- Product descriptionAdapalene
- Packaging50mg
- Price$50
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AHH | API-1690 | Adapalene 98% | 1g | $610 | 2021-12-16 | Buy |
| AK Scientific | I810 | Adapalene | 100mg | $39 | 2021-12-16 | Buy |
| AK Scientific | J50424 | Adapalene | 250mg | $45 | 2021-12-16 | Buy |
| AK Scientific | I810 | Adapalene | 250mg | $61 | 2021-12-16 | Buy |
| AK Scientific | J50424 | Adapalene | 1g | $125 | 2021-12-16 | Buy |
| AK Scientific | I810 | Adapalene | 1g | $167 | 2021-12-16 | Buy |
| AK Scientific | I810 | Adapalene | 10g | $667 | 2021-12-16 | Buy |
| Alfa Aesar | J67025 | Adapalene | 25mg | $117 | 2021-12-16 | Buy |
| Alfa Aesar | J67025 | Adapalene | 50mg | $144 | 2021-12-16 | Buy |
| Ambeed | A105293 | 6-(3-(Adamantan-1-yl)-4-methoxyphenyl)-2-naphthoicacid 99+% | 50mg | $6 | 2021-12-16 | Buy |
| Ambeed | A105293 | 6-(3-(Adamantan-1-yl)-4-methoxyphenyl)-2-naphthoicacid 99+% | 100mg | $10 | 2021-12-16 | Buy |
| Ambeed | A105293 | 6-(3-(Adamantan-1-yl)-4-methoxyphenyl)-2-naphthoicacid 99+% | 250mg | $13 | 2021-12-16 | Buy |
| Ambeed | A105293 | 6-(3-(Adamantan-1-yl)-4-methoxyphenyl)-2-naphthoicacid 99+% | 1g | $13 | 2021-12-16 | Buy |
| Ambeed | A105293 | 6-(3-(Adamantan-1-yl)-4-methoxyphenyl)-2-naphthoicacid 99+% | 25g | $441 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0001385 | Adapalene 95.00% | 0.25G | $407 | 2021-12-16 | Buy |
| ApexBio Technology | A1267 | Adapalene | 50mg | $50 | 2021-12-16 | Buy |
Properties
Melting point :319-3220C
Boiling point :606.3±55.0 °C(Predicted)
Density :1.233±0.06 g/cm3(Predicted)
RTECS :QJ1987000
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
pka :4.2(at 25℃)
form :White solid
color :white to off-white
Merck :14,150
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 3 months
InChIKey :LZCDAPDGXCYOEH-UHFFFAOYSA-N
SMILES :C1=C2C(C=C(C3=CC=C(OC)C(C45CC6CC(CC(C6)C4)C5)=C3)C=C2)=CC=C1C(O)=O
CAS DataBase Reference :106685-40-9(CAS DataBase Reference)
Boiling point :606.3±55.0 °C(Predicted)
Density :1.233±0.06 g/cm3(Predicted)
RTECS :QJ1987000
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
pka :4.2(at 25℃)
form :White solid
color :white to off-white
Merck :14,150
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 3 months
InChIKey :LZCDAPDGXCYOEH-UHFFFAOYSA-N
SMILES :C1=C2C(C=C(C3=CC=C(OC)C(C45CC6CC(CC(C6)C4)C5)=C3)C=C2)=CC=C1C(O)=O
CAS DataBase Reference :106685-40-9(CAS DataBase Reference)
Safety Information
| Symbol(GHS): |
|
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | ||||||||||||
| Hazard statements: |
|
||||||||||||
| Precautionary statements: |
|
Description
Adapalene, a synthetic naphthoic acid derivative, is a selective agonist of retinoic acid receptor (RAR)-β and RAR-γ (Kds = 34 and 130 nM, respectively). At 0.1-10 μM, adapalene dose-dependently inhibits sebocyte growth, proliferation, and differentiation in a primary rat preputial cell culture system. Adapalene demonstrates anti-inflammatory and immunomodulatory activity by inhibiting 5-lipoxygenase-catalyzed leukotriene production and expression of toll-like receptor 2 on human monocytes. It is commonly used for the study of the pathogenesis and treatment of acne vulgaris.Related product price
- Anisic acid
$6-5679 - Amantadine
$41-5445 - Naphthalene
$16-491
Suppliers and manufacturers
Changsha Junyu Chemexpress.co., Ltd
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd
Beijing Cooperate Pharmaceutical Co.,Ltd
