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ChemicalBook >> CAS DataBase List >> (2E)-3-(1H-Imidazole-4-yl)propenoic acid

(2E)-3-(1H-Imidazole-4-yl)propenoic acid

(2E)-3-(1H-Imidazole-4-yl)propenoic acid price.
  • $37 - $1170
  • Product name: (2E)-3-(1H-Imidazole-4-yl)propenoic acid
  • CAS: 3465-72-3
  • MF: C6H6N2O2
  • MW: 138.12
  • EINECS:203-258-4
  • MDL Number:MFCD00005203
  • Synonyms:(2E)-3-(1H-Imidazole-4-yl)acrylic acid;(2E)-3-(1H-Imidazole-4-yl)propenoic acid;(E)-3-(1H-Imidazol-4-yl)propenoic acid;(E)-Urocanic acid;(αE)-1H-Imidazole-4-acrylic acid;trans-Urocanic acid;(2E)-3-(1H-Imidazol-4-yl)acrylic acid;(2E)-3-(1H-Imidazol-4-yl)prop-2-enoic acid
10 prices
Selected condition：
Brand
  • AK Scientific
  • Alichem
  • Cayman Chemical
  • Crysdot
  • Matrix Scientific
  • TCI Chemical
  • TRC
Package
  • 1g
  • 5g
  • 10g
  • 100g
  • ManufacturerAK Scientific
  • Product number1024CG
  • Product descriptioncis-Urocanic acid
  • Packaging5g
  • Price$213
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number3465723
  • Product description(E)-3-(1H-Imidazol-5-yl)acrylicacid
  • Packaging100g
  • Price$718.2
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16228
  • Product descriptiontrans-Urocanic Acid ≥98%
  • Packaging1g
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16228
  • Product descriptiontrans-Urocanic Acid ≥98%
  • Packaging5g
  • Price$134
  • Updated2024-03-01
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11139103
  • Product description(E)-3-(1H-Imidazol-5-yl)acrylicacid 95+%
  • Packaging100g
  • Price$665
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number176213
  • Product description(E)-3-(1H-Imidazol-4-yl)-2-propenoic acid
  • Packaging1g
  • Price$316
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number176213
  • Product description(E)-3-(1H-Imidazol-4-yl)-2-propenoic acid
  • Packaging5g
  • Price$810
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number176213
  • Product description(E)-3-(1H-Imidazol-4-yl)-2-propenoic acid
  • Packaging10g
  • Price$1170
  • Updated2021-12-16
  • Buy
  • ManufacturerTCI Chemical
  • Product numberI0002
  • Product descriptiontrans-Urocanic Acid >98.0%(HPLC)(T)
  • Packaging5g
  • Price$135
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberI577448
  • Product description(E)-3-(1H-Imidazol-5-yl)acrylicAcid
  • Packaging5g
  • Price$65
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1024CG cis-Urocanic acid 5g $213 2021-12-16 Buy
Alichem 3465723 (E)-3-(1H-Imidazol-5-yl)acrylicacid 100g $718.2 2021-12-16 Buy
Cayman Chemical 16228 trans-Urocanic Acid ≥98% 1g $37 2024-03-01 Buy
Cayman Chemical 16228 trans-Urocanic Acid ≥98% 5g $134 2024-03-01 Buy
Crysdot CD11139103 (E)-3-(1H-Imidazol-5-yl)acrylicacid 95+% 100g $665 2021-12-16 Buy
Matrix Scientific 176213 (E)-3-(1H-Imidazol-4-yl)-2-propenoic acid 1g $316 2021-12-16 Buy
Matrix Scientific 176213 (E)-3-(1H-Imidazol-4-yl)-2-propenoic acid 5g $810 2021-12-16 Buy
Matrix Scientific 176213 (E)-3-(1H-Imidazol-4-yl)-2-propenoic acid 10g $1170 2021-12-16 Buy
TCI Chemical I0002 trans-Urocanic Acid >98.0%(HPLC)(T) 5g $135 2024-03-01 Buy
TRC I577448 (E)-3-(1H-Imidazol-5-yl)acrylicAcid 5g $65 2021-12-16 Buy

Properties

Melting point :225 °C
Boiling point :456.9±20.0 °C(Predicted)
Density :1.430±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMF: 3 mg/ml; DMSO: 15 mg/ml; PBS (pH 7.2): 0.3 mg/ml
form :powder to crystal
pka :3.55±0.10(Predicted)
color :White to Almost white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

trans-Urocanic acid is a major epidermal chromophore for the immunosuppressive effects of UV radiation that is produced in mammalian stratum corneum by the action of histidine ammonialyase on L-histidine. It contributes to the acidification of the surface of the stratum corneum, and its function has been proposed as that of an endogenous sunscreen, endowing a low-level of protection (SPF ~ 1.5) against UV-induced DNA damage and excessive keratinocyte apoptosis. Upon UVB exposure, trans-urocanic acid is converted to the cis isomer, which is known to activate regulatory T cells.

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