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ChemicalBook >> CAS DataBase List >> N-(2-[P-BROMOCINNAMYLAMINO]ETHYL)-5-ISOQUINOLINESULFONAMIDE HYDROCHLORIDE

N-(2-[P-BROMOCINNAMYLAMINO]ETHYL)-5-ISOQUINOLINESULFONAMIDE HYDROCHLORIDE

N-(2-[P-BROMOCINNAMYLAMINO]ETHYL)-5-ISOQUINOLINESULFONAMIDE HYDROCHLORIDE price.
  • $43 - $1529
  • Product name: N-(2-[P-BROMOCINNAMYLAMINO]ETHYL)-5-ISOQUINOLINESULFONAMIDE HYDROCHLORIDE
  • CAS: 127243-85-0
  • MF: C20H20BrN3O2S
  • MW: 446.36
  • EINECS:
  • MDL Number:MFCD00214119
  • Synonyms:H-89;H-89 DIHYDROCHLORIDE;H-89 HYDROCHLORIDE;N-[2-(P-BROMOCINNAMYLAMINO)ETHYL]-5-ISOQUINOLINE SULFONAMIDE;N-[2-(P-BROMOCINNAMYLAMINO)ETHYL]-5-ISOQUINOLINESULFONAMIDE 2HCL;N-[2-(P-BROMOCINNAMYLAMINO)ETHYL]-5-ISOQUINOLINE SULFONAMIDE, DIHYDROCHLORIDE;N-(2-[P-BROMOCINNAMYLAMINO]ETHYL)-5-ISOQUINOLINESULFONAMIDE HYDROCHLORIDE;N-[2-[P-BROMOCINNAMYLAMINO]-ETHYL]-5-ISOQUINOLINESULFONMIDE
19 prices
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Brand
  • American Custom Chemicals Corporation
  • Biosynth Carbosynth
  • Chemenu
  • Crysdot
  • CSNpharm
  • Medical Isotopes, Inc.
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 1
  • 5mg
  • 50
  • 10MG
  • 25MG
  • 50mg
  • 100MG
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000906
  • Product descriptionH-89 95.00%
  • Packaging10MG
  • Price$664.82
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000906
  • Product descriptionH-89 95.00%
  • Packaging25MG
  • Price$766.69
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000906
  • Product descriptionH-89 95.00%
  • Packaging100MG
  • Price$1203.28
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB19217
  • Product descriptionN-[2-(p-Bromocinnamylamino)ethyl]-5-isoquinoline sulfonamide
  • Packaging5mg
  • Price$140
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB19217
  • Product descriptionN-[2-(p-Bromocinnamylamino)ethyl]-5-isoquinoline sulfonamide
  • Packaging10mg
  • Price$254.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB19217
  • Product descriptionN-[2-(p-Bromocinnamylamino)ethyl]-5-isoquinoline sulfonamide
  • Packaging25mg
  • Price$463
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB19217
  • Product descriptionN-[2-(p-Bromocinnamylamino)ethyl]-5-isoquinoline sulfonamide
  • Packaging50mg
  • Price$841.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB19217
  • Product descriptionN-[2-(p-Bromocinnamylamino)ethyl]-5-isoquinoline sulfonamide
  • Packaging100mg
  • Price$1529
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM145787
  • Product descriptionN-(2-((3-(4-Bromophenyl)allyl)amino)ethyl)isoquinoline-5-sulfonamide 98%
  • Packaging100mg
  • Price$261
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004022
  • Product descriptionH89 98+%
  • Packaging100mg
  • Price$279
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004022
  • Product descriptionH89 98+%
  • Packaging50mg
  • Price$166
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004022
  • Product descriptionH89 98+%
  • Packaging10mg
  • Price$43
  • Updated2021-12-16
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN11132
  • Product descriptionH89
  • Packaging10mg
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number7731
  • Product descriptionN-[2-(p-Bromocinnamylamino)ethyl]-5-IsoquinolineSulfonamide
  • Packaging10mg
  • Price$830
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number2910
  • Product descriptionH89dihydrochloride ≥98%(HPLC)
  • Packaging1
  • Price$93
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number2910
  • Product descriptionH89dihydrochloride ≥98%(HPLC)
  • Packaging10
  • Price$203
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation KIN0000906 H-89 95.00% 10MG $664.82 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000906 H-89 95.00% 25MG $766.69 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000906 H-89 95.00% 100MG $1203.28 2021-12-16 Buy
Biosynth Carbosynth FB19217 N-[2-(p-Bromocinnamylamino)ethyl]-5-isoquinoline sulfonamide 5mg $140 2021-12-16 Buy
Biosynth Carbosynth FB19217 N-[2-(p-Bromocinnamylamino)ethyl]-5-isoquinoline sulfonamide 10mg $254.5 2021-12-16 Buy
Biosynth Carbosynth FB19217 N-[2-(p-Bromocinnamylamino)ethyl]-5-isoquinoline sulfonamide 25mg $463 2021-12-16 Buy
Biosynth Carbosynth FB19217 N-[2-(p-Bromocinnamylamino)ethyl]-5-isoquinoline sulfonamide 50mg $841.5 2021-12-16 Buy
Biosynth Carbosynth FB19217 N-[2-(p-Bromocinnamylamino)ethyl]-5-isoquinoline sulfonamide 100mg $1529 2021-12-16 Buy
Chemenu CM145787 N-(2-((3-(4-Bromophenyl)allyl)amino)ethyl)isoquinoline-5-sulfonamide 98% 100mg $261 2021-12-16 Buy
Crysdot CD31004022 H89 98+% 100mg $279 2021-12-16 Buy
Crysdot CD31004022 H89 98+% 50mg $166 2021-12-16 Buy
Crysdot CD31004022 H89 98+% 10mg $43 2021-12-16 Buy
CSNpharm CSN11132 H89 10mg $55 2021-12-16 Buy
Medical Isotopes, Inc. 7731 N-[2-(p-Bromocinnamylamino)ethyl]-5-IsoquinolineSulfonamide 10mg $830 2021-12-16 Buy
Tocris 2910 H89dihydrochloride ≥98%(HPLC) 1 $93 2021-12-16 Buy
Tocris 2910 H89dihydrochloride ≥98%(HPLC) 10 $203 2021-12-16 Buy

Properties

Melting point :195-200°C
Boiling point :639.7±65.0 °C(Predicted)
Density :1.436
storage temp. :2-8°C
solubility :H2O: ≥10 mg/mL
form :powder
pka :10.43±0.50(Predicted)
color :off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
CAS DataBase Reference :127243-85-0(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H312 Harmful in contact with skin Acute toxicity,dermal Category 4 Warning GHS hazard pictograms P280,P302+P352, P312, P322, P363,P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P322 Specific measures (see …on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P363 Wash contaminated clothing before reuse.
P501 Dispose of contents/container to..…

Description

H-89, Dihydrochloride is a cell-permeable, non-selective, reversible, ATP-competitive, potent inhibitor of PKA (cyclic AMP-dependent protein kinase). PKA regulates glycogen, sugar and lipid metabolism and plays an important role in the cell cycle. H-89, once thought to be a selective PKA inhibitor, has been shown to also inhibit CaM kinase II, casein kinase I, Rsk-2 (MAPKAP-K1b), MSK1, MYLK (myosin light chain kinase), Akt1 (PKB α), PKC μ, Rock-2 (ROCK-II) and p70 S6 kinase α.

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