5-(4-[4-cyanobut-1-ynyl]phenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(1,1-dioxo-thiomorpholino)-1H-pyrazole-3-carboxamide
![5-(4-[4-cyanobut-1-ynyl]phenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(1,1-dioxo-thiomorpholino)-1H-pyrazole-3-carboxamide price.](/CAS/20180703/GIF/1245626-05-4.gif)
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- $44 - $961
- Product name: 5-(4-[4-cyanobut-1-ynyl]phenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(1,1-dioxo-thiomorpholino)-1H-pyrazole-3-carboxamide
- CAS: 1245626-05-4
- MF: C26H23Cl2N5O3S
- MW: 556.46
- EINECS:
- MDL Number:MFCD19053178
- Synonyms:5-(4-[4-cyanobut-1-ynyl]phenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(1,1-dioxo-thiomorpholino)-1H-pyrazole-3-carboxamide;AM6545;5-[4-(4-Cyano-1-butyn-1-yl)phenyl]-1-(2,4-dichlorophenyl)-N-(1,1-dioxido-4-thiomorpholinyl)-4-methyl-1H-pyrazole-3-carboxamide;1H-Pyrazole-3-carboxamide, 5-[4-(4-cyano-1-butyn-1-yl)phenyl]-1-(2,4-dichlorophenyl)-N-(1,1-dioxido-4-thiomorpholinyl)-4-methyl-;AM-6545,AM6545
15 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- Sigma-Aldrich
- Tocris
- TRC
Package
- 10
- 5MG
- 1mg
- 50
- 10mg
- 25mg
- ManufacturerAK Scientific
- Product number9177BB
- Product descriptionCID46912919
- Packaging10mg
- Price$360
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number9177BB
- Product descriptionCID46912919
- Packaging25mg
- Price$691
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0005735
- Product descriptionAM 6545 95.00%
- Packaging5MG
- Price$459.43
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC4711
- Product descriptionAM6545
- Packaging5mg
- Price$182
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC4711
- Product descriptionAM6545
- Packaging10mg
- Price$268
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC4711
- Product descriptionAM6545
- Packaging25mg
- Price$608
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16316
- Product descriptionAM6545 ≥98%
- Packaging1mg
- Price$44
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16316
- Product descriptionAM6545 ≥98%
- Packaging5mg
- Price$161
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16316
- Product descriptionAM6545 ≥98%
- Packaging10mg
- Price$235
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16316
- Product descriptionAM6545 ≥98%
- Packaging25mg
- Price$533
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberA1987
- Product descriptionAM6545 ≥98% (HPLC)
- Packaging5mg
- Price$276
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberA1987
- Product descriptionAM6545 ≥98% (HPLC)
- Packaging25mg
- Price$878
- Updated2024-03-01
- Buy
- ManufacturerTocris
- Product number5443
- Product descriptionAM6545 ≥98%(HPLC)
- Packaging10
- Price$229
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number5443
- Product descriptionAM6545 ≥98%(HPLC)
- Packaging50
- Price$961
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberA575945
- Product descriptionAM6545
- Packaging1mg
- Price$55
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 9177BB | CID46912919 | 10mg | $360 | 2021-12-16 | Buy |
| AK Scientific | 9177BB | CID46912919 | 25mg | $691 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0005735 | AM 6545 95.00% | 5MG | $459.43 | 2021-12-16 | Buy |
| ApexBio Technology | C4711 | AM6545 | 5mg | $182 | 2021-12-16 | Buy |
| ApexBio Technology | C4711 | AM6545 | 10mg | $268 | 2021-12-16 | Buy |
| ApexBio Technology | C4711 | AM6545 | 25mg | $608 | 2021-12-16 | Buy |
| Cayman Chemical | 16316 | AM6545 ≥98% | 1mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 16316 | AM6545 ≥98% | 5mg | $161 | 2024-03-01 | Buy |
| Cayman Chemical | 16316 | AM6545 ≥98% | 10mg | $235 | 2024-03-01 | Buy |
| Cayman Chemical | 16316 | AM6545 ≥98% | 25mg | $533 | 2024-03-01 | Buy |
| Sigma-Aldrich | A1987 | AM6545 ≥98% (HPLC) | 5mg | $276 | 2024-03-01 | Buy |
| Sigma-Aldrich | A1987 | AM6545 ≥98% (HPLC) | 25mg | $878 | 2024-03-01 | Buy |
| Tocris | 5443 | AM6545 ≥98%(HPLC) | 10 | $229 | 2021-12-16 | Buy |
| Tocris | 5443 | AM6545 ≥98%(HPLC) | 50 | $961 | 2021-12-16 | Buy |
| TRC | A575945 | AM6545 | 1mg | $55 | 2021-12-16 | Buy |
Properties
storage temp. :2-8°C
solubility :DMSO: >25mg/mL
form :powder
color :white to off-white
solubility :DMSO: >25mg/mL
form :powder
color :white to off-white
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Peripherally-restricted cannabinoid receptor 1 (CB1) selective antagonists have the potential to inhibit food intake while also escaping centrally-mediated neuropsychiatric side effects. AM6545 is a novel CB1 selective neutral antagonist with low CNS penetration, exhibiting Ki values of 1.7 and 523 nM for CB1 and CB2 receptors, respectively. It reduces food intake and food-reinforced behavior, such as time spent feeding, in a dose-dependent manner, resulting in decreased body weight. AM6545 produces improvements in glucose homeostasis, fatty liver, and plasma lipid profiles in mice with diet-induced obesity. It does not affect behavior responses that are associated with activation of CB1 receptors in the brain.Suppliers and manufacturers
Career Henan Chemica Co
Wuhan Topule Biopharmaceutical Co., Ltd
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd
Aladdin Scientific
Shanghai EFE Biological Technology Co., Ltd.
Shanghai Chaolan Chemical Technology Center
BOC Sciences
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
ShangHai ChuanQian Chemcial Technique Centre
