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ChemicalBook >> CAS DataBase List >> N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-1,3,5-triazine-2,4-diamine

N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-1,3,5-triazine-2,4-diamine

N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-1,3,5-triazine-2,4-diamine price.
  • $39 - $12210
  • Product name: N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-1,3,5-triazine-2,4-diamine
  • CAS: 1097917-15-1
  • MF: C29H40N8O3S
  • MW: 580.74
  • EINECS:200-258-5
  • MDL Number:MFCD21609265
  • Synonyms:ASP3026;ASP 3026;ASP-3026;N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfon;ASP 3026;N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-1,3,5-triazine-2,4-diamine;1,3,5-Triazine-2,4-diamine, N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-;N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-1,3,5-triazine-2,4-diamine ASP 3026;ASP 3026; ASP-3026;CS-286
28 prices
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Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Axon Medchem
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Tocris
  • TRC
  • Usbiological
Package
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  • 1MG
  • 5MG
  • 10
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  • 25mg
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  • 100mg
  • 250mg
  • 1000mg
  • 1g
  • 5g
  • ManufacturerAK Scientific
  • Product numberSYN5648
  • Product descriptionASP3026
  • Packaging10mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001435
  • Product descriptionASP-3026 95.00%
  • Packaging1MG
  • Price$480
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001435
  • Product descriptionASP-3026 95.00%
  • Packaging5MG
  • Price$786.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001435
  • Product descriptionASP-3026 95.00%
  • Packaging10MG
  • Price$866.25
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001435
  • Product descriptionASP-3026 95.00%
  • Packaging50MG
  • Price$1374.45
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3193
  • Product descriptionASP3026
  • Packaging50mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2005
  • Product descriptionASP3026 99%
  • Packaging5mg
  • Price$121
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181196
  • Product descriptionASP3026 >98%
  • Packaging100mg
  • Price$615.4
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181196
  • Product descriptionASP3026 >98%
  • Packaging250mg
  • Price$1208.7
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181196
  • Product descriptionASP3026 >98%
  • Packaging1000mg
  • Price$2395.3
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number18491
  • Product descriptionASP3026 ≥98%
  • Packaging1mg
  • Price$39
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18491
  • Product descriptionASP3026 ≥98%
  • Packaging5mg
  • Price$96
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18491
  • Product descriptionASP3026 ≥98%
  • Packaging10mg
  • Price$152
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18491
  • Product descriptionASP3026 ≥98%
  • Packaging25mg
  • Price$331
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0787
  • Product descriptionASP3026 99.90%
  • Packaging50mg
  • Price$240
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0787
  • Product descriptionASP3026 99.90%
  • Packaging100mg
  • Price$400
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific SYN5648 ASP3026 10mg $160 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001435 ASP-3026 95.00% 1MG $480 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001435 ASP-3026 95.00% 5MG $786.5 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001435 ASP-3026 95.00% 10MG $866.25 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001435 ASP-3026 95.00% 50MG $1374.45 2021-12-16 Buy
ApexBio Technology A3193 ASP3026 50mg $300 2021-12-16 Buy
Axon Medchem Axon2005 ASP3026 99% 5mg $121 2021-12-16 Buy
Biorbyt Ltd orb181196 ASP3026 >98% 100mg $615.4 2021-12-16 Buy
Biorbyt Ltd orb181196 ASP3026 >98% 250mg $1208.7 2021-12-16 Buy
Biorbyt Ltd orb181196 ASP3026 >98% 1000mg $2395.3 2021-12-16 Buy
Cayman Chemical 18491 ASP3026 ≥98% 1mg $39 2024-03-01 Buy
Cayman Chemical 18491 ASP3026 ≥98% 5mg $96 2024-03-01 Buy
Cayman Chemical 18491 ASP3026 ≥98% 10mg $152 2024-03-01 Buy
Cayman Chemical 18491 ASP3026 ≥98% 25mg $331 2024-03-01 Buy
ChemScene CS-0787 ASP3026 99.90% 50mg $240 2021-12-16 Buy
ChemScene CS-0787 ASP3026 99.90% 100mg $400 2021-12-16 Buy

Properties

Boiling point :794.3±70.0 °C(Predicted)
Density :1.276
storage temp. :Store at -20°C
solubility :insoluble in H2O; ≥14.53 mg/mL in DMSO; ≥4.9 mg/mL in EtOH with gentle warming and ultrasonic
form :solid
pka :8.14±0.42(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

ASP3026 is an ATP-competitive, second-generation ALK inhibitor (IC50 = 3.5 nM) that also inhibits ROS (IC50 = 8.9 nM) and ACK (IC50 = 5.8 nM). It inhibits neuroblastoma-activating ALK mutants F1174L (IC50 = 10 nM) and R1275Q (IC50 = 5.4 nM) and demonstrates antitumor activity in xenograft mouse models. ASP3026 has been shown to overcome crizotinib resistance in non-small cell lung cancer, and is currently being evaluated in clinical trials of patients with ALK-positive solid tumors.

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