Sotalol suppliers
Sotalol
- CAS:
- 3930-20-9
- MF:
- C12H20N2O3S
- MW:
- 272.36
Suppliers by country/region
Company Type
Properties
- Melting point:
- 206.5-207 °C
- Boiling point:
- 443.3±55.0 °C(Predicted)
- Density
- 1.298 g/cm3
- storage temp.
- Hygroscopic, -20°C Freezer, Under inert atmosphere
- solubility
- Chloroform (Slightly, Heated), Methanol (Slightly, Sonicated)
- pka
- pK1 8.2, pK2 9.8(at 25℃)
- form
- Solid
- color
- Pale Yellow to Light Yellow
- BCS Class
- 1
- Stability:
- Hygroscopic
- InChI
- InChI=1S/C12H20N2O3S/c1-9(2)13-8-12(15)10-4-6-11(7-5-10)14-18(3,16)17/h4-7,9,12-15H,8H2,1-3H3
- InChIKey
- ZBMZVLHSJCTVON-UHFFFAOYSA-N
- SMILES
- CS(NC1=CC=C(C(O)CNC(C)C)C=C1)(=O)=O
- CAS DataBase Reference
- 3930-20-9(CAS DataBase Reference)
- NIST Chemistry Reference
- Methanesulfonanilide, 4'-(1-hydroxy-2-(isopropylamino)ethyl)-(3930-20-9)
- EPA Substance Registry System
- Methanesulfonamide, N-[4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]phenyl]- (3930-20-9)
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H319
- Precautionary statements
- P305+P351+P338
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36
Use
The sotalol enantiomers produce different effects onthe heart. Class III action of d-sotalol in the sinus node isassociated with slowing of sinus heart rate, whereas -adrenergicblockade contributes to the decrease in heart rate observedwith 1- or d,1-sotalol. Sotalol is not metabolized, noris it bound significantly to proteins. Elimination occurs byrenal excretion, with more than 80% of the drug eliminatedunchanged. Sotalol is characteristic of class III antiarrhythmicdrugs, in that it prolongs the duration of the action potentialand, thus, increases the effective refractory period of myocardialtissue. It is distinguished from the other class III drugs(amiodarone and bretylium) because of its -adrenergicreceptor–blocking action.
58 supplier list of "Sotalol"
$0.00-0.00 / 1kg
- Product Name:Sotalol
- Products Intro:Purity: 99%|Package: 1kg;0.00;USD|25kg;0.00;USD|50kg;0.00;USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 6108-05-0,59-46-1,58-20-8,136-47-0,148553-50-8

-
100mg$239.00250mg$382.001g$955.00
- Product Name:Sotalol
- Products Intro:Brand:Crysdot | Product Number:CD31002005 | Purity:95+%
- Company Type: Trader
- Country/Region: UNITED STATES

-
1g$893.00
- Product Name:N-(4-(1-Hydroxy-2-(isopropylamino)ethyl)phenyl)methanesulfonamide
- Products Intro:Brand:Chemenu | Product Number:CM276444 | Purity:95%
- Company Type: Trader
- Country/Region: UNITED STATES