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DOTA

DOTA ??? ???
?? ??:
60239-18-1
???:
DOTA
???(??):
TETRAXETAN;1,4,7,10-TETRAAZACYCLODODECANE-1,4,7,10-TETRAACETIC ACID;2,2',2'',2'''-(1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrayl)tetraacetic acid;DOTA;98% DOTA;TETRAAZA;DOTADOTA;NSC 681107;DOTA, ≥97%;DOTA(M-140)
CBNumber:
CB9398467
???:
C16H28N4O8
??? ??:
404.42
MOL ??:
60239-18-1.mol
MSDS ??:
SDS

DOTA ??

???
267 °C
?? ?
701.6±60.0 °C(Predicted)
??
1.321
?? ??
Sealed in dry,Room Temperature
???
?(??, ??), ???(??)? ???
?? ?? (pKa)
2.16±0.10(Predicted)
??? ??
??
??
???
BRN
1186987
???
???
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi
?? ???? ?? 36/37/38
????? 26-36
WGK ?? 3
F ?????? 3-10-34
HS ?? 29339900
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
NFPA 704
0
2 0

DOTA C??? ??, ??, ??

??? ??

Colourless crystals

??

Bifunctional DOTA aconjugates to peptides and has become an established strategy for constructing target-specific metal containing agents including targeted MRI contrast agents and diagnostic and ther apeutic radiopharmaceuticals.

??

ChEBI: An azamacrocyle in which four nitrogen atoms at positions 1, 4, 7 and 10 of a twelve-membered ring are each substituted with a carboxymethyl group.

DOTA ?? ?? ? ???

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DOTA ?? ??

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DOTA ?? ??:

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