ChemicalBook >?? ???? >1,3-?????????
1,3-?????????
|
|
1,3-????????? ??
- ???
- 121-123 °C (lit.) 121-123 °C
- ?? ?
- 228.1±23.0 °C(Predicted)
- ??
- 1.322±0.06 g/cm3(Predicted)
- ?? ??
- 500kg/m3
- ?? ??
- -20°C Freezer
- ???
- ??? ?: ???0.5g/10mL, ??, ?? ?? ??? ???
- ??? ??
- ??? ??
- ?? ?? (pKa)
- pK1:4.68(+1) (25°C)
- ??
- ???/??/?? ???
- ??????(pH)
- 2.5 (20°C, 100g/L in H2O, slurry)
- ???
- ?? ?????.
- BRN
- 139810
- CAS ??????
- 769-42-6(CAS DataBase Reference)
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
1,3-????????? C??? ??, ??, ??
??? ??
Yellow or brownish powder??
1,3-Dimethylbarbituric acid is used as a catalyst in the Knoevenagel condensation of a series of aromatic aldehydes. It is also used in the synthesis of 5-aryl-6-(alkyl- or aryl-amino)-1,3-dimethylfuro [2,3-d]pyrimidine derivatives and enantioselective synthesis of isochromene pyrimidinedione derivatives.?? ??
1,3-Dimethylbarbituric acid (1,3-Dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione) is an active methylene compound. It undergoes hollow Pd6 water-soluble cage, [{(tmen)Pd}6(timb)4](NO3)12 (tmen= N,N,N′,N′-tetramethylethylenediamine, timb=1,3,5-tris(1-imidazolyl)benzene)-catalyzed Knoevenagel condensation reaction with pyrene-1-carboxaldehyde. It undergoes self-sorted Pd7 molecular boat having an internal nanocavity (catalyst)-assisted Knoevenagel condensation reaction with various aromatic aldehydes. It has been synthesized by reacting 1,3-dimethylurea, malonic acid and acetic anhydride in acetic acid. It is widely used for the synthesis of various synthetic intermediates and heterocyclic compounds.Purification Methods
Crystallise the acid from water and sublime it in a vacuum. Also purify it by dissolving 10g in 100mL of boiling CCl4/CHCl3 (8:2) (1g charcoal), filtering and cooling to 25o. Dry it in vacuo [Kohn et al. Anal Chem 58 3184 1986]. [Beilstein 24 III/IV 1875.]1,3-????????? ?? ?? ? ???
???
?? ??
6-[N-(2-Hydroxyethyl)amino]-1,3-dimethyl-2,4(1H,3H)-dione
ISOCAFFEINE
1,3-dimethyl-5-(thiophen-2-ylmethylene)pyrimidine-2,4,6(1H,3H,5H)-trione
7-AMINO-1,3-DIMETHYL-2,4-DIOXO-1,2,3,4-TETRAHYDRO-5H-PYRANO[2,3-D]PYRIMIDINE-5,5,6-TRICARBONITRILE
5-((1H-indol-3-yl)methylene)-1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione
2-[(1,3-dimethyl-2,4,6-trioxo-1,3-diazinan-5-ylidene)methyl]phenyl acetate
1,3-dimethyl-5-[(4-oxo-4H-chromen-3-yl)methylidene]-1,3-diazinane-2,4,6-trione
1,3-DIMETHYL-5-([4-(METHYLSULFANYL)PHENYL]METHYLENE)-2,4,6(1H,3H,5H)-PYRIMIDINETRIONE
6-chloro-1,3-dimethyl-5-nitro-pyrimidine-2,4-quinone
1,3-DIMETHYL-5-[(DIMETHYLAMINO)METHYLENE]2,4,6-(1H,3H,5H)-TRIOXOPRYIMIDINE
1,3-????????? ?? ??
???( 401)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
| weifang runzhong fine chemical co., ltd | 536-7868377 +8618653686003 |
sq@runzhongchem.com | China | 187 | 58 |
| Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 |
sales@hbmojin.com | China | 12809 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 |
deasea125996@gmail.com | China | 2472 | 58 |
| Wuhan Quanjinci New Material Co.,Ltd. | +86-15271838296; +8615271838296 |
kyra@quanjinci.com | China | 1512 | 58 |
| ShenZhen H&D Pharmaceutical Technology Co., LTD | +8618627948422 |
sale@hdimpurity.com | China | 3619 | 58 |
| HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | +8615350851019 |
admin@86-ss.com | China | 1001 | 58 |
| Shandong Huizhihan Supply Chain Co., Ltd | +86-13363081709 +86-13363000288 |
3957328362@qq.com | China | 300 | 58 |
| Hebei Junhua Import and Export Co., LTD | +86-18503288844 +86-18503288844 |
junhua1@hb-junhua.com | China | 978 | 58 |
| Chongqing Soarwin Technology Co., Ltd | +86-19132938950 +86-19132938950 |
crystal@sorawin.cn | China | 360 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21628 | 55 |