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- >163° (dec.)
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- 490.7±45.0 °C(Predicted)
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- 1.160±0.06 g/cm3(Predicted)
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- Refrigerator
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- 13.81±0.20(Predicted)
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Originator
Bucumarol,Sankyo,Japan,1982Manufacturing Process
A mixture of 3 g of 8-(2-hydroxy-3-chloropropoxy)-5-methyl coumarin, 4.3 g of t-butylamine and 60 ml of ethanol is heated at 100°C in a sealed tube for 15 hours. The reaction mixture is concentrated under reduced pressure to dryness. The residue is recrystallized from a mixture of ethanol and ether to give 2.1 g of the desired product melting at 226° to 228°C (with decomposition).In practice it is usually used as hydrochloride.
Therapeutic Function
Beta-adrenergic blocker???? ?? ?? ? ???
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| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28172 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 32268 | 58 |
| Hubei Nordina Biotechnology Co., Ltd. | 19371278702 |
China | 277 | 58 | |
| TargetMol Chemicals Inc. | 15002134094 |
marketing@targetmol.cn | China | 19956 | 58 |
| Biosynth Biological Technology (Suzhou) Co Ltd | 51288865780 |
sales@biosynth.com | China | 233051 | 58 |