????????
???????? ??
???
245-246 °C(lit.)
??
1.5484 (estimate)
?? ??
Sealed in dry,Store in freezer, under -20°C
???
???: ???50mg/mL, ??
??? ??
powder to crystal
?? ?? (pKa)
6.63±0.10(Predicted)
??
White to Orange to Green
???
???
BRN
612694
InChI
InChI=1S/C5H3F3N2O2/c6-5(7,8)2-1-9-4(12)10-3(2)11/h1H,(H2,9,10,11,12)
InChIKey
LMNPKIOZMGYQIU-UHFFFAOYSA-N
SMILES
C1(=O)NC=C(C(F)(F)F)C(=O)N1
CAS ??????
54-20-6(CAS DataBase Reference)
NIST
2,4(1H,3h)-pyrimidinedione, 5-(trifluoromethyl)-(54-20-6)
??
?? ? ?? ??
?? ? ???? ?? (GHS)
??? ??
Xi,T
?? ???? ??
22-36/38-40-36/37/38-25
?????
24/25-36-26
????(UN No.)
2811
WGK ??
3
RTECS ??
YR1750000
?? ?? ??
Irritant
?? ??
6.1
????
Ⅲ
HS ??
29335990
??
LD50 intraperitoneal in mouse: 800mg/kg
????(GHS):
?? ?:
Danger
??·?? ??:
??
??·?? ??
?? ??
??
?? ?
?? ??
P- ??
H301
??? ???
?? ?? ?? - ??
?? 3
??
P264, P270, P301+P310, P321, P330,P405, P501
H315
??? ??? ???
????? ?? ?????
?? 2
??
P264, P280, P302+P352, P321,P332+P313, P362
H319
?? ?? ??? ???
?? ? ?? ?? ??? ??
?? 2A
??
P264, P280, P305+P351+P338,P337+P313P
H335
?? ???? ??? ? ??
?? ???? ?? - 1? ??;???? ??
?? 3
??
??????:
P302+P352
??? ??? ??? ?? ????.
P305+P351+P338
?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
NFPA 704
???????? C??? ??, ??, ??
??? ??
White to faintly yellow crystalline powder
?? ??
Trifluorothymine (5-(Trifluoromethyl)uracil) is an application medicine intermediate widely. It may be used for the synthesis of the cancer therapy drug trifluridine and also can be used for the preparation of the 2, 4-dichloro-5-trifluoromethyluracil.
???????? ?? ?? ? ???
???
?? ??
???????? ?? ??
???( 388)?? ??
Belgium 2
Canada 1
China 282
France 2
Germany 11
India 19
Italy 1
Japan 5
Slovakia 1
Switzerland 2
United Kingdom 17
United States 45
Global 388
???
??
???
??
?? ?
??
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