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Vagistat

Vagistat ??? ???
?? ??:
65899-73-2
???:
Vagistat
???(??):
Trosyl;Trosyd;Zoniden;vagistat;UK-20349;Fungibacid;Vagistat 1;ioconazole;Gyno-Trosyd;TIOCONAZOLE
CBNumber:
CB8416704
???:
C16H13Cl3N2OS
??? ??:
387.71
MOL ??:
65899-73-2.mol
MSDS ??:
SDS

Vagistat ??

???
79-81oC
?? ?
534.5±50.0 °C(Predicted)
??
1.3115 (rough estimate)
???
1.6000 (estimate)
RTECS ??
NI4480000
?? ??
Keep in dark place,Inert atmosphere,Room temperature
???
?? ?? ?? ????, ?????? ?? ????, ????? ? ?????.
?? ?? (pKa)
6.66±0.12(Predicted)
??? ??
??
??
???? ?????
CAS ??????
65899-73-2(CAS DataBase Reference)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xn
?? ???? ?? 22
WGK ?? 3
HS ?? 2934990002
????(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P264, P270, P301+P312, P330, P501
H317 ????? ?? ??? ??? ? ?? ?? ??? ?? ?? 1 ?? GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H410 ??? ??? ?? ????? ?? ??? ?? ????? ?? - ?? ?? 1 ?? GHS hazard pictograms P273, P391, P501
??????:
P202 ?? ?? ?? ??? ?? ???? ??? ???? ???.
P273 ???? ???? ???.
P280 ????/???/???/?????? ?????.
P301+P312 ??? ???? ??? ????(??)? ??? ????.
P302+P352 ??? ??? ??? ?? ????.
P308+P313 ?? ?? ??? ???? ???? ??· ??? ????.
NFPA 704
0
2 0

Vagistat C??? ??, ??, ??

??

Tioconazole is an antifungal agent, closely related to miconazole. Tioconazole is effective in the topical treatment of superficial fungal infections and appears to be more potent than miconazole against Candida and Trichophyton species.

??? ??

White powder EINECS: 265-973-8

??

antithrombotic

??

ChEBI: A member of the class of imidazoles that comprises 2-(2,4-dichlorophenyl)ethylimidazole carrying an additional (2-chloro-3-thienyl)methoxy substituent at position 2.

Antimicrobial activity

Tioconazole is a broad-spectrum imidazole antimycotic with activity against almost all species of pathogenic fungi.

Clinical Use

1-[2-[(2-chloro-3-thienyl)methoxy]2-(2,4-dichlorophenyl)-ethyl]-1H-imidazole (Vagistat) is used for the treatment ofvulvovaginal candidiasis. A vaginal ointment containing6.5% of the free base is available. Tioconazole is more effectiveagainst Torulopsis glabrata than are other azoles.

Vagistat ?? ?? ? ???

???

?? ??


Vagistat ?? ??

???( 281)?? ??
??? ?? ??? ?? ?? ? ??
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Vagistat ?? ??:

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