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2-Piperidinecarboxylic acid, 1-(3,3-dimethyl-1,2-dioxopentyl)-, (1R)-1-[3-[[3-[2-[2-[[2-[[1-(2-chloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl]oxy]acetyl]amino]ethoxy]ethoxy]-1-oxopropyl]amino]phenyl]-3-(3,4-dimethoxyphenyl)propyl ester, (2S)-

2-Piperidinecarboxylic acid, 1-(3,3-dimethyl-1,2-dioxopentyl)-, (1R)-1-[3-[[3-[2-[2-[[2-[[1-(2-chloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl]oxy]acetyl]amino]ethoxy]ethoxy]-1-oxopropyl]amino]phenyl]-3-(3,4-dimethoxyphenyl)propyl ester, (2S)- ??? ???
?? ??:
2384184-40-9
???:
2-Piperidinecarboxylic acid, 1-(3,3-dimethyl-1,2-dioxopentyl)-, (1R)-1-[3-[[3-[2-[2-[[2-[[1-(2-chloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl]oxy]acetyl]amino]ethoxy]ethoxy]-1-oxopropyl]amino]phenyl]-3-(3,4-dimethoxyphenyl)propyl ester, (2S)-
???(??):
KB02-SLF;(1R)-1-[3-(3-{2-[2-(2-{[1-(2-chloroacetyl)-1,2,3,4-tetrahydroquinolin-6-yl]oxy}acetamido)ethoxy]ethoxy}propanamido)phenyl]-3-(3,4-dimethoxyphenyl)propyl (2S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carboxylate;2-Piperidinecarboxylic acid, 1-(3,3-dimethyl-1,2-dioxopentyl)-, (1R)-1-[3-[[3-[2-[2-[[2-[[1-(2-chloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl]oxy]acetyl]amino]ethoxy]ethoxy]-1-oxopropyl]amino]phenyl]-3-(3,4-dimethoxyphenyl)propyl ester, (2S)-;(R)-1-(3-(3-(2-(2-(2-((1-(2-Chloroacetyl)-1,2,3,4-tetrahydroquinolin-6-yl)oxy)acetamido)ethoxy)ethoxy)propanamido)phenyl)-3-(3,4-dimethoxyphenyl)propyl (S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carboxylate, Electrophilic PROTAC?, Heterobifunctional conjugate for E3 ubiquitin ligase discovery
CBNumber:
CB78227385
???:
C50H65ClN4O12
??? ??:
949.52
MOL ??:
2384184-40-9.mol

2-Piperidinecarboxylic acid, 1-(3,3-dimethyl-1,2-dioxopentyl)-, (1R)-1-[3-[[3-[2-[2-[[2-[[1-(2-chloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl]oxy]acetyl]amino]ethoxy]ethoxy]-1-oxopropyl]amino]phenyl]-3-(3,4-dimethoxyphenyl)propyl ester, (2S)- ??

??
1.240±0.06 g/cm3(Predicted)
?? ??
4°C, away from moisture and light
???
DMSO : 100 mg/mL (105.32 mM; Need ultrasonic)
?? ?? (pKa)
14.03±0.46(Predicted)
??? ??
Solid
??
White to yellow

??

2-Piperidinecarboxylic acid, 1-(3,3-dimethyl-1,2-dioxopentyl)-, (1R)-1-[3-[[3-[2-[2-[[2-[[1-(2-chloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl]oxy]acetyl]amino]ethoxy]ethoxy]-1-oxopropyl]amino]phenyl]-3-(3,4-dimethoxyphenyl)propyl ester, (2S)- C??? ??, ??, ??

2-Piperidinecarboxylic acid, 1-(3,3-dimethyl-1,2-dioxopentyl)-, (1R)-1-[3-[[3-[2-[2-[[2-[[1-(2-chloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl]oxy]acetyl]amino]ethoxy]ethoxy]-1-oxopropyl]amino]phenyl]-3-(3,4-dimethoxyphenyl)propyl ester, (2S)- ?? ?? ? ???

???

?? ??


2-Piperidinecarboxylic acid, 1-(3,3-dimethyl-1,2-dioxopentyl)-, (1R)-1-[3-[[3-[2-[2-[[2-[[1-(2-chloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl]oxy]acetyl]amino]ethoxy]ethoxy]-1-oxopropyl]amino]phenyl]-3-(3,4-dimethoxyphenyl)propyl ester, (2S)- ?? ??

???( 8)?? ??
??? ?? ??? ?? ?? ? ??
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