Anti-solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 C??? ??, ??, ??

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Solute carrier family 9 member 7 (SLC9A7), also called sodium/hydrogen exchanger 7 (NHE7), is a 80 kDa protein present in trans-Golgi complex. It is a sodium/hydrogen exchanger with N-terminal membrane spanning region and C-terminal hydrophilic tail. SLC9A7 is mapped to human chromosome Xp11.3.

Biochem/physiol Actions

SLC9A7 (NHE7) is a sodium and potassium/ proton antiporter belonging to the solute carrier family 9 protein family. It is localized to trans-Golgi network and mediates the influx of Na+ or K+ in exchange for H+. NHE7 binds with SCAMP2, a member of the secretory carrier membrane protein (SCAMP) gene family. SCAMP2 reportedly aids the shuttling of NHE7 between recycling vesicles and the trans-Golgi network.

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Anti-solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 ?? ??

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