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2-ThiophenecarboxaMide, 5-chloro-N-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-Morpholinyl)phenyl]aMino]propyl]-

2-ThiophenecarboxaMide, 5-chloro-N-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-Morpholinyl)phenyl]aMino]propyl]- ??? ???
?? ??:
721401-53-2
???:
2-ThiophenecarboxaMide, 5-chloro-N-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-Morpholinyl)phenyl]aMino]propyl]-
???(??):
Rivaroxaban L;Rivaroxaban-12;Decarbonyl Rivaroxaban;Rivaroxaban ImpuritiesG;Rivaroxaban Impurities358;Rivaroxaban impurity P4D-P;Rivaroxaban Impurity 17 CRS;Rivaroxaban Related Impurity G;Rivaroxaban Descarbonyl Impurity;Rivaroxaban descarbonyl imp(G) (pure)
CBNumber:
CB72707359
???:
C18H20ClN3O4S
??? ??:
409.89
MOL ??:
721401-53-2.mol

2-ThiophenecarboxaMide, 5-chloro-N-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-Morpholinyl)phenyl]aMino]propyl]- ??

???
>188°C (dec.)
?? ?
772.6±60.0 °C(Predicted)
??
1.434±0.06 g/cm3(Predicted)
?? ??
under inert gas (nitrogen or Argon) at 2–8 °C
???
DMSO(?? ???), ???(?? ???)
?? ?? (pKa)
13.65±0.46(Predicted)
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??
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2-ThiophenecarboxaMide, 5-chloro-N-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-Morpholinyl)phenyl]aMino]propyl]- C??? ??, ??, ??

??

Decarbonyl Rivaroxaban is an impurity of Rivaroxaban (R538000), which is a novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor.

2-ThiophenecarboxaMide, 5-chloro-N-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-Morpholinyl)phenyl]aMino]propyl]- ?? ?? ? ???

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2-ThiophenecarboxaMide, 5-chloro-N-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-Morpholinyl)phenyl]aMino]propyl]- ?? ??

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