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1,5,6,7-???????-4H-??-4-?

1,5,6,7-???????-4H-??-4-?
1,5,6,7-???????-4H-??-4-? ??? ???
?? ??:
13754-86-4
???:
1,5,6,7-???????-4H-??-4-?
???(??):
1,5,6,7-???????-4H-??-4-?
???:
1,5,6,7-TETRAHYDRO-4H-INDOL-4-ONE
???(??):
NSC 131681;Tetrahydroindolone;4-0xo-4,5,6,7-tetr;1,5,6,7-Tetrahydro-4H<;6,7-Dihydroindol-4(5H)-one;4,5,6,7-Tetrahydro-4-indolone;4,5,6,7-Tetrahydro-4-oxoindole;4-0xo-4,5,6,7-tetrahydroindole;4-OXO-4,5,6,7-TETRAHYDROINDOLE;1,5,6,7-TETRAHYDRO-INDOL-4-ONE
CBNumber:
CB7265060
???:
C8H9NO
??? ??:
135.16
MOL ??:
13754-86-4.mol
MSDS ??:
SDS

1,5,6,7-???????-4H-??-4-? ??

???
188-190 °C (lit.)
?? ?
311℃
??
1.216
???
150℃
?? ??
under inert gas (nitrogen or Argon) at 2–8 °C
??? ??
powder to crystal
?? ?? (pKa)
15.91±0.20(Predicted)
??
White to Light yellow to Light orange
CAS ??????
13754-86-4(CAS DataBase Reference)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi
?? ???? ?? 36/37/38
????? 26-37/39
WGK ?? 3
HS ?? 2914390090
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P271 ?? ?? ??? ? ?? ???? ?????.
P280 ????/???/???/?????? ?????.
P302+P352 ??? ??? ??? ?? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

1,5,6,7-???????-4H-??-4-? C??? ??, ??, ??

??

1,5,6,7-Tetrahydro-4H-indol-4-one, is a versatile building block used for the synthesis of more complex pharmaceutical compounds. It can be used for the preparation of Psammopemmin A.

?? ??

Iodination of 1,5,6,7-tetrahydro-4H-indol-4-one using 1-chloromethyl--4-fluoro-1,4-diazoniabicyclo[2.2.2]octane bis(tetra-fluoroborate) yields α-iodo derivative as the main product.

1,5,6,7-???????-4H-??-4-? ?? ?? ? ???

???

?? ??


1,5,6,7-???????-4H-??-4-? ?? ??

???( 161)?? ??
??? ?? ??? ?? ?? ? ??
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