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9-OXO-15S-HYDROXY-PROSTA-5Z,10,13E,17Z-TETRAEN-1-OIC ACID

9-OXO-15S-HYDROXY-PROSTA-5Z,10,13E,17Z-TETRAEN-1-OIC ACID ??? ???
?? ??:
36614-31-0
???:
9-OXO-15S-HYDROXY-PROSTA-5Z,10,13E,17Z-TETRAEN-1-OIC ACID
???(??):
PGA3;PROSTAGLANDIN A3;KSIRMUMXJFWKAC-FHJHOUOTSA-N;Recombinant Human Pepsin A-3/PGI/PGA3 Protein, His Tag;9-OXO-15S-HYDROXY-PROSTA-5Z,10,13E,17Z-TETRAEN-1-OIC ACID;(5Z,13E,15S,17Z)-15-Hydroxy-9-oxoprosta-5,10,13,17-tetraen-1-oic acid;Prosta-5,10,13,17-tetraen-1-oic acid, 15-hydroxy-9-oxo-, (5Z,13E,15S,17Z)-;7-[(1R,2S)-2-[(3S)-3-hydroxyocta-1,5-dienyl]-5-oxocyclopent-3-en-1-yl]hept-5-enoic acid
CBNumber:
CB7189005
???:
C20H28O4
??? ??:
332.43
MOL ??:
36614-31-0.mol

9-OXO-15S-HYDROXY-PROSTA-5Z,10,13E,17Z-TETRAEN-1-OIC ACID ??

?? ??
-20°C
???
DMF: >75 mg/ml (from PGA1); DMSO: >50 mg/ml (from PGA1); Ethanol: >100 mg/ml (from PGA1); PBS pH 7.2: >2.4 mg/ml (from PGA1)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
????(GHS): GHS hazard pictogramsGHS hazard pictograms
?? ?: Danger
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H225 ???? ?? ? ?? ??? ?? ?? 2 ?? GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H336 ?? ?? ???? ??? ? ?? ?????? ?? ??(1? ??);???? ?? 3 ?? P261, P271, P304+P340, P312,P403+P233, P405, P501
??????:
P210 ?·???·??·????? ????? - ?? ???.
P240 ??? ????? ?? ? ??????.
P241 ?? ??? ??[???/??/??/...]?(?) ?????.
P242 ???? ???? ?? ??? ?????
P243 ??? ?? ??? ????.
P261 ??·?·??·???·??·...·????? ??? ????.
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P271 ?? ?? ??? ? ?? ???? ?????.
P280 ????/???/???/?????? ?????.
P303+P361+P353 ??(?? ????)? ??? ??? ?? ??? ??? ????? ??? ?? ????/?????.
P304+P340 ???? ??? ??? ?? ??? ??? ???? ?? ??? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P312 ???? ??? ????(??)? ??? ????.
P337+P313 ?? ?? ??? ???? ???? ??· ??? ????.
P370+P378 ?? ? ?? ?? ?? (Section 5. ??, ??? ????? ??? ???)?(?) ?????.
P403+P233 ??? ??? ? ?? ?? ??? ???? ?????.
P403+P235 ??? ? ?? ?? ???? ???? ?????.
P405 ???? ?????.
P501 ...? ??? / ??? ?? ???.
NFPA 704
3
2 0

9-OXO-15S-HYDROXY-PROSTA-5Z,10,13E,17Z-TETRAEN-1-OIC ACID C??? ??, ??, ??

??

Cyclooxygenase metabolism of EPA to produce Prostaglandin E3 (PGE3) has been reported in biosynthetic preparations of ovine seminal vesicles and in the ocular tissues of primates. Prostaglandin A3 (PGA3) is an expected non-enzymatic dehydration product of this PGE3. PGA3 exhibits good affinity for the canine EP2 and EP4 receptors with IC50 values of 120 nM and 20 nM, respectively, in a radioligand binding assay. PGA3 has weak affinity for human PPARγ, with a Ki value of 188 μM.

9-OXO-15S-HYDROXY-PROSTA-5Z,10,13E,17Z-TETRAEN-1-OIC ACID ?? ?? ? ???

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9-OXO-15S-HYDROXY-PROSTA-5Z,10,13E,17Z-TETRAEN-1-OIC ACID ?? ??

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??? ?? ??? ?? ?? ? ??
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