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51-67-2
???:
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???(??):
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???:
Tyramine
???(??):
51-67-2;4-(2-AMINOETHYL)PHENOL;p-Tyramine;L-TYRAMINE;4-(2-aminoethyl)-pheno;PHENOL, 4-(2-AMINOETHYL)-;p-Hydroxyphenylethylamine;8-[3;4-Hyd;Tyramin
CBNumber:
CB7152784
???:
C8H11NO
??? ??:
137.18
MOL ??:
51-67-2.mol
MSDS ??:
SDS

??? ??

???
160-162 °C(lit.)
?? ?
175-181 °C8 mm Hg(lit.)
??
1.0630 (rough estimate)
???
1.5849 (estimate)
FEMA
4215 | TYRAMINE
???
165°C
?? ??
2-8°C
???
DMSO(?? ???), ???(?? ???)
??? ??
??
?? ?? (pKa)
9.74(at 25℃)
??
??? ????? ????? ?? ????, ?? ? ???? ? ??
??
100.00%??. ?? ?? ?? ??? ?? ??? ?? ??
?? ??
??? ??
???? ??
synthetic
???
1g/95mL(15℃)
Merck
14,9835
JECFA Number
1590
BRN
1099914
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????. ??, ????? ???? ????.
LogP
1.38
CAS ??????
51-67-2(CAS DataBase Reference)
NIST
Phenol, 4-(2-aminoethyl)-(51-67-2)
EPA
Tyramine (51-67-2)
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  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi
?? ???? ?? 36/37/38
????? 26-36-37/39
WGK ?? 3
RTECS ?? SJ5950000
F ?????? 10-23
HS ?? 29214990
?? ?? ??? 51-67-2(Hazardous Substances Data)
?? LD50 intracervical in mouse: 30mg/kg
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P271 ?? ?? ??? ? ?? ???? ?????.
P280 ????/???/???/?????? ?????.
P302+P352 ??? ??? ??? ?? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
NFPA 704
0
2 0

??? MSDS


4-(2-Aminoethyl)phenol

??? C??? ??, ??, ??

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A decarboxylation product of tyrosine found in various fermentation products, including cheeses and some wines. It causes sympathomimetic effects by acting as an indirect agonist, causing the release of endogenous catecholamines. Because it is metabolized principally by monoamine oxidase, patients taking monoamine oxidase inhibitors may have a hypertensive crisis if they ingest foods containing significant amounts of tyramine.

??? ??

white to light beige solid

??

Reported found in sauerkraut and soy sauce.

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tyramine is uses as pharmaceutical intermediates.

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ChEBI: A primary amino compound obtained by formal decarboxylation of the amino acid tyrosine.

Purification Methods

Crystallise tyramine from *benzene or EtOH. [Beilstein 13 IV 1788.]

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