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2-Methyl-2-thiopseudourea sulfate

2-Methyl-2-thiopseudourea sulfate ??? ???
?? ??:
867-44-7
???:
2-Methyl-2-thiopseudourea sulfate
???(??):
S-MethyliSothourea Sulfate;S-Methyl isothiourea sulfate;methylsulfanylmethanimidamide;s-methylthiouroniumsulfate(2:1);methylcarbamimidothioate sulfate;S-Methyl-ITU;S-METHYLTHIOUREA;S-EIT hemihydrate;isothiouronium suL;2-Methyl-2-thiopseud
CBNumber:
CB7105816
???:
C2H8N2O4S2
??? ??:
188.23
MOL ??:
867-44-7.mol
MSDS ??:
SDS

2-Methyl-2-thiopseudourea sulfate ??

???
240-241 °C (dec.)(lit.)
??
1.28
???
3℃
?? ??
Inert atmosphere,Room Temperature
???
H2O: 0.1 g/mL, ??, ??
??? ??
?? ?? ??? ??
?? ?? (pKa)
pK1:9.83(＋1) (25°C)
??
???
??????(pH)
5.5 (260g/l, H2O, 20℃)
???
260g/L(20℃)
??
Hygroscopic
BRN
3917217
???
????. ?? ???? ???? ????.
CAS ??????
867-44-7(CAS DataBase Reference)
EPA
Carbamimidothioic acid, methyl ester, sulfate (2:1) (867-44-7)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xn
?? ???? ?? 22
????? 22-24/25
WGK ?? 3
RTECS ?? UM9200000
TSCA Yes
HS ?? 29309070
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P264, P270, P301+P312, P330, P501
??????:
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P270 ? ??? ??? ??? ???, ???? ???? ???.
P330 ?? ?????.
NFPA 704
1
2 0

2-Methyl-2-thiopseudourea sulfate MSDS


2-Methyl-2-thiopseudourea sulfate

2-Methyl-2-thiopseudourea sulfate C??? ??, ??, ??

??

SMIT is a potent non-selective inhibitor of NOS isoforms in vitro but may lack good in vivo efficacy due to poor cellular penetration. The Ki values are 120, 200, and 160 nM using purified human iNOS, eNOS, and nNOS, respectively.

??? ??

white crystalline powder

??

Intermediate of 4-Hydroxydebrisoquine. S-Methyl-isothiouronium Hemisulfate is also a reagent used in the synthesis of strobilurin-pyrimidine derivatives for their anti-proliferative activity.

2-Methyl-2-thiopseudourea sulfate ?? ?? ? ???

???

?? ??

5-[2-(????)????-4-YL]???-2-?????? 5-CHLORO-2-(METHYLSULFONYL)PYRIMIDINE-4-CARBOXYLIC ACID 4-Methoxy-6-methyl-2-(methylthio)pyrimidine 4-METHYL-2-METHYLSULFANYL-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER N-??-N'-???-N-???????? ethyl 2-(methylsulfanyl)-4-(trifluoromethyl)pyrimidine-5-carboxylate 2-(METHYLTHIO)ETHANOL 5-METHYL-2-METHYLSULFANYL-PYRIMIDINE S-????????????? Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate 5-BROMO-2-(METHYLSULFONYL)PYRIMIDINE-4-CARBOXYLIC ACID 4-MORPHOLINECARBOXAMIDINE 5-???-2-(????)????-4-????? 5-Bromo-4-chloro-2-(methylthio)-7H-pyrrolo[2,3-D]pyrimidine ,97% 5-CHLORO-2-METHOXYPYRIMIDINE-4-CARBOXYLIC ACID ?????????? ???????? METHYL 5-BROMO-2-(METHYLSULFANYL)-4-PYRIMIDINECARBOXYLATE, 97 ETHYL 2-(ETHYLTHIO)-4-HYDROXYPYRIMIDINE-5-CARBOXYLATE 5-Chloro-2-(methylsulfonyl)pyrimidine 2-(METHYLTHIO)-4-(TRIFLUOROMETHYL)PYRIMIDINE 5-methoxy-2-(methylthio)pyrimidin-4-ol ,97% 4-Methoxy-6-methyl-2-(methylsulfonyl)pyrimidine ,97% 1,1-DIMETHYLGUANIDINE SULFATE 3-OXO-3-???-2-YL-??????????? 4-AMINO-2-METHYLSULFANYL-PYRIMIDINE-5-CARBOXYLIC ACID 4-(Trifluoromethyl)-2-(methylthio)pyrimidine-5-carboxylic acid ,97% 4-Chloro-2-(methylthio)pyrimidine-5-carbonitrile ,97% 1-(4-??-2-(????)????-5-?)??? 4-Chloro-6-methyl-2-(methylthio)pyrimidine 2-(?????)-5-?????? 5-Methyl-2-(methylsulfonyl)pyrimidine ,97% 4-?????-2-(????)????-5-????? 1,4-DIHYDRO-2-(????)-4-OXO-5-????-??????????? IMINOCTADINE TRIACETATE 6-Methyl-2-(methylthio)pyrimidin-4-ol ETHYL 4-AMINO-2-(METHYLTHIO)PYRIMIDINE-5-CARBOXYLATE 5-AMINOPYRIMIDINE 5-Chloro-2-(methylthio)pyrimidine-4-carboxylic acid Aminoguanidinium sulphate

2-Methyl-2-thiopseudourea sulfate ?? ??

???( 462)?? ??
??? ?? ??? ?? ?? ? ??
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2-Methyl-2-thiopseudourea sulfate ?? ??:

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