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D-KYNURENINE

D-KYNURENINE ??? ???
?? ??:
13441-51-5
???:
D-KYNURENINE
???(??):
D-KYNURENINE;D-Kynurenine sulfate;D-Kynurenine;REF DUPL: D-Kynurenine;D-kynurenine free base;D-KYNURENINE USP/EP/BP;β-Anthraniloyl-D-alanine;beta-Anthraniloyl-D-alanine;(R)-α,2-Diamino-γ-oxobenzenebutanoic acid;R-2-Amino-4-[2-aminophenyl]-4-oxobutanoic acid
CBNumber:
CB6475231
???:
C10H12N2O3
??? ??:
208.21
MOL ??:
13441-51-5.mol

D-KYNURENINE ??

?? ?
466.6±45.0 °C(Predicted)
??
1.343±0.06 g/cm3(Predicted)
?? ??
2-8°C
???
Water:5.0(Max Conc. mg/mL);24.01(Max Conc. mM)
??? ??
??? ??
?? ?? (pKa)
2.21±0.23(Predicted)
??
Light yellow to yellow
CAS ??????
13441-51-5(CAS DataBase Reference)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
WGK ?? 3
HS ?? 29225000
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P271 ?? ?? ??? ? ?? ???? ?????.
P280 ????/???/???/?????? ?????.

D-KYNURENINE C??? ??, ??, ??

??

D-Kynurenine is a metabolite of D-tryptophan that is also a bioprecursor of two neuroactive compounds kynurenic acid (KYNA) and 3-hydroxykynurenine.

??

ChEBI: A kynurenine that has D configuration.

Biochem/physiol Actions

D-Kynurenine may be used along with L-kynurenine to assess the specificity and kinetics of kynurenine metabolizing enzymes. D-Kynurenine is used to study the selectivity and activity of the G protein-coupled receptor, GPR109B. D-Kynurenine is used as a substrate in a fluorometric assay of D-amino acid oxidase.

D-KYNURENINE ?? ?? ? ???

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D-KYNURENINE ?? ??

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D-KYNURENINE ?? ??:

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